Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ITGB3 | P05106 | 12/20 | 0.40 |
| ▸ | ITGA2B | P08514 | 9/20 | 0.40 |
| ▸ | ITGAV | P06756 | 6/20 | 0.40 |
| ▸ | BRD4 | O60885 | 1/20 | 0.37 |
| ▸ | MAPT | P10636 | 5/20 | 0.36 |
| ▸ | MEN1 | O00255 | 2/20 | 0.36 |
| ▸ | TP53 | P04637 | 2/20 | 0.36 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.36 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.36 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.36 |
| ▸ | HPGD | P15428 | 1/20 | 0.36 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7596369 | 0.87 | ITGB3 (0.53) | ITGB3ITGA2BITGAVBRD4 | |
| SCHEMBL7595704 | 0.87 | ITGB3 (0.54) | ITGB3ITGA2BITGAVMAPTTP53 | |
| SCHEMBL7399604 | 0.82 | ITGB3 (0.52) | ITGB3ITGA2BITGAVALDH1A1HPGD | |
| SCHEMBL7402544 | 0.74 | ITGB3 (0.46) | ITGB3ITGA2BITGAVALDH1A1HPGD | |
| SCHEMBL7395726 | 0.73 | ITGB3 (0.69) | ITGB3ITGA2BITGAV | |
| SCHEMBL7595687 | 0.73 | ITGB3 (0.69) | ITGB3ITGA2BITGAV | |
| SCHEMBL7594819 | 0.71 | ITGB3 (0.78) | ITGB3ITGA2BITGAV | |
| SCHEMBL7397921 | 0.71 | ITGB3 (0.49) | ITGB3ITGA2BITGAVBRD4MAPT | |
| SCHEMBL6952593 | 0.70 | ITGB3 (0.77) | ITGB3ITGA2BITGAV | |
| Hydrochloric Acid SCHEMBL3042381 | 0.69 | ITGB3 (0.76) | ITGB3ITGA2BITGAV |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0593603-B1 | BICYCLIC FIBRINOGEN ANTAGONISTS | SMITHKLINE BEECHAM CORP (US) | 2002-11-20 | — | — | EP | disclosed |