Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 2/20 | 0.34 |
| ▸ | BLM | P54132 | 2/20 | 0.34 |
| ▸ | MEN1 | O00255 | 1/20 | 0.34 |
| ▸ | HBB | P68871 | 1/20 | 0.34 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.34 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.34 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.33 |
| ▸ | ALOX15 | P16050 | 2/20 | 0.33 |
| ▸ | EYA2 | O00167 | 1/20 | 0.33 |
| ▸ | APP | P05067 | 1/20 | 0.33 |
| ▸ | ACE | P12821 | 1/20 | 0.33 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.33 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.32 |
| ▸ | CHRM2 | P08172 | 1/20 | 0.32 |
| ▸ | ADRA2A | P08913 | 1/20 | 0.32 |
| ▸ | TSHR | P16473 | 1/20 | 0.32 |
| ▸ | DRD1 | P21728 | 1/20 | 0.32 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.32 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.32 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4860492 | 0.98 | LMNA (0.36) | LMNABLMMEN1HBBKMT2A | |
| SCHEMBL4860482 | 0.98 | LMNA (0.36) | LMNABLMMEN1HBBKMT2A | |
| SCHEMBL4860473 | 0.98 | LMNA (0.36) | LMNABLMMEN1HBBKMT2A | |
| SCHEMBL14066120 | 0.98 | LMNA (0.36) | LMNABLMMEN1HBBKMT2A | |
| SCHEMBL6013898 | 0.74 | CYP3A4 (0.35) | LMNAALOX15CYP3A4 | |
| SCHEMBL29956579 | 0.73 | — | — | |
| SCHEMBL15406522 | 0.67 | MAPT (0.39) | TDP1ALOX15CYP3A4KDM4E | |
| SCHEMBL18229249 | 0.66 | TDP1 (0.45) | LMNABLMHIF1ATDP1ALOX15 | |
| SCHEMBL6323180 | 0.66 | TDP1 (0.45) | LMNABLMHIF1ATDP1ALOX15 | |
| SCHEMBL6518392 | 0.66 | TDP1 (0.45) | LMNABLMHIF1ATDP1ALOX15 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6491617-B1 | Medical devices that resist restenosis | ST. JUDE MEDICAL, INC. | 2002-12-10 | — | — | US | disclosed |
| EP-1251901-A1 | MEDICAL DEVICES THAT RESIST RESTENOSIS | ST. JUDE MEDICAL, INC. (US) | 2002-10-30 | — | — | EP | disclosed |
| WO-2001049358-A1 | MEDICAL DEVICES THAT RESIST RESTENOSIS | ST. JUDE MEDICAL, INC. (US) | 2001-07-12 | — | — | WO | disclosed |