SCHEMBL7596802

SCHEMBL7596802

O=C(O)OC1c2ccccc2-c2ccccc21

nearest known ligand 0.52

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
POLB P06746 1/20 0.52
HDAC3 O15379 1/20 0.44
HDAC4 P56524 1/20 0.44
HDAC7 Q8WUI4 1/20 0.44
HDAC8 Q9BY41 1/20 0.44
HDAC6 Q9UBN7 1/20 0.44
HDAC9 Q9UKV0 1/20 0.44
HDAC5 Q9UQL6 1/20 0.44
NCOR2 Q9Y618 1/20 0.44
CYP1A2 P05177 1/20 0.42
TSHR P16473 1/20 0.42
EDNRA P25101 2/20 0.41
EDNRB P24530 1/20 0.41
MAPT P10636 1/20 0.41
KMT2A Q03164 2/20 0.39
FABP7 O15540 1/20 0.37
FABP5 Q01469 1/20 0.37
GAA P10253 1/20 0.37
CACNA1G O43497 1/20 0.36
MEN1 O00255 1/20 0.36

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Succinimide SCHEMBL9461462 0.85 TSHR (0.43) POLBCYP1A2TSHREDNRAEDNRB
SCHEMBL27777776 0.84 POLB (0.53) POLBHDAC3HDAC4HDAC7HDAC8
SCHEMBL21778844 0.83 F2 (0.50) POLBTSHRMAPTKMT2AGAA
SCHEMBL20917779 0.83 POLB (0.52) POLBHDAC3HDAC4HDAC7HDAC8
SCHEMBL643958 0.81 POLB (0.50) POLBHDAC3HDAC4HDAC7HDAC8
SCHEMBL30341829 0.81 POLB (0.71) POLBHDAC3HDAC4HDAC7HDAC8
SCHEMBL4402923 0.81 POLB (0.71) POLBHDAC3HDAC4HDAC7HDAC8
SCHEMBL931810 0.81 POLB (0.50) POLBHDAC3HDAC4HDAC7HDAC8
SCHEMBL7532314 0.81 POLB (0.50) POLBHDAC3HDAC4HDAC7HDAC8
SCHEMBL10442104 0.80 LRRK2 (0.43) POLBEDNRAEDNRBMAPTKMT2A

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 21 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-3681629-B1 PALLADIUM-BASED ACETYLENE SELECTIVE HYDROGENATION CATALYSTS ENHANCED BY ORGANIC DOPANTS CHEVRON PHILLIPS CHEMICAL CO LP (US) 2021-11-24 EP claimed
EP-3039069-B1 MODIFIED EPOXIDISED NATURAL RUBBER MICHELIN & CIE (FR) 2018-07-25 EP claimed
EP-0110432-B1 PROCESS FOR PREPARING 9-FLUORENECARBOXYLIC ACID RÜTGERSWERKE AKTIENGESELLSCHAFT (DE) 1985-12-04 EP claimed
EP-0110432-A1 Process for preparing 9-fluorenecarboxylic acid RÜTGERSWERKE AKTIENGESELLSCHAFT (DE) 1984-06-13 EP claimed
CN-110105434-B Stapled and stitched polypeptides and uses thereof 哈佛大学的校长及成员们 2024-09-17 CN disclosed
CN-111936487-B Compounds for the treatment of kinase dependent disorders 埃克塞里艾克西斯公司 2024-07-09 CN disclosed
CN-112312909-B Compounds for the treatment of kinase dependent disorders 埃克塞里艾克西斯公司 2024-07-02 CN disclosed
CN-117412761-A Antibody drug conjugates for delivery of cytotoxic agents using MATE technology 拜奥海芬治疗学有限公司 2024-01-16 CN disclosed
CN-116940679-A Oligomeric compounds for dystrophin rescue in DMD patients by skipping of exon-51 SQY治疗公司 2023-10-24 CN disclosed
CN-111163771-B Use of pyrimidopyrimidinones as SIK inhibitors 通用医疗公司 2023-07-14 CN disclosed
CN-116113621-A Amino acids 弗格制药有限公司 2023-05-12 CN disclosed
CN-110869544-A Cyclic peptide compound having high membrane permeability and library containing same 中外制药株式会社 2020-03-06 CN disclosed
EP-0874281-B1 Chemically amplified resist INFINEON TECHNOLOGIES AG (DE) 2002-12-04 EP disclosed
EP-0874281-A1 Chemically amplified resist SIEMENS AKTIENGESELLSCHAFT (DE) 1998-10-28 EP disclosed
EP-0608198-A1 Cyclic diphenylacetonenitriles as stabilisers CIBA-GEIGY AG (CH) 1994-07-27 EP disclosed
EP-0110432-B1 PROCESS FOR PREPARING 9-FLUORENECARBOXYLIC ACID RÜTGERSWERKE AKTIENGESELLSCHAFT (DE) 1985-12-04 EP disclosed
EP-0110432-B1 PROCESS FOR PREPARING 9-FLUORENECARBOXYLIC ACID RÜTGERSWERKE AKTIENGESELLSCHAFT (DE) 1985-12-04 EP disclosed
EP-0110432-A1 Process for preparing 9-fluorenecarboxylic acid RÜTGERSWERKE AKTIENGESELLSCHAFT (DE) 1984-06-13 EP disclosed
EP-0110432-A1 Process for preparing 9-fluorenecarboxylic acid RÜTGERSWERKE AKTIENGESELLSCHAFT (DE) 1984-06-13 EP disclosed
EP-0110432-A1 Process for preparing 9-fluorenecarboxylic acid RÜTGERSWERKE AKTIENGESELLSCHAFT (DE) 1984-06-13 EP disclosed