SCHEMBL931810

SCHEMBL931810

O=C(Cl)OC1c2ccccc2-c2ccccc21

nearest known ligand 0.50

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
POLB P06746 1/20 0.50
HDAC3 O15379 2/20 0.42
HDAC6 Q9UBN7 2/20 0.42
HDAC4 P56524 1/20 0.42
HDAC7 Q8WUI4 1/20 0.42
HDAC8 Q9BY41 1/20 0.42
HDAC9 Q9UKV0 1/20 0.42
HDAC5 Q9UQL6 1/20 0.42
NCOR2 Q9Y618 1/20 0.42
KMT2A Q03164 2/20 0.38
CYP1A2 P05177 1/20 0.37
TSHR P16473 1/20 0.37
SLC6A4 P31645 1/20 0.37
SLC6A3 Q01959 1/20 0.37
EDNRB P24530 1/20 0.36
EDNRA P25101 1/20 0.36
MAPT P10636 1/20 0.36
GAA P10253 1/20 0.36
CACNA1G O43497 1/20 0.36
ALDH1A1 P00352 1/20 0.35

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL27777776 0.83 POLB (0.53) POLBHDAC3HDAC6HDAC4HDAC7
SCHEMBL28897874 0.82 POLB (0.42) POLBHDAC3HDAC6HDAC4HDAC7
SCHEMBL20917779 0.81 POLB (0.52) POLBHDAC3HDAC6HDAC4HDAC7
SCHEMBL7596802 0.81 POLB (0.52) POLBHDAC3HDAC6HDAC4HDAC7
SCHEMBL4402923 0.79 POLB (0.71) POLBHDAC3HDAC6HDAC4HDAC7
SCHEMBL30341829 0.79 POLB (0.71) POLBHDAC3HDAC6HDAC4HDAC7
SCHEMBL7532314 0.79 POLB (0.50) POLBHDAC3HDAC6HDAC4HDAC7
SCHEMBL643958 0.79 POLB (0.50) POLBHDAC3HDAC6HDAC4HDAC7
SCHEMBL21778856 0.79 POLB (0.46) POLBHDAC3HDAC6HDAC4HDAC7
SCHEMBL7837312 0.79 ATM (0.50) HDAC3HDAC6HDAC4HDAC7HDAC8

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 117 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-113292456-B Preparation method of N-fluorenylmethoxycarbonyl-L-aspartic acid-4-tert-butyl ester 常州吉恩药业有限公司 2022-04-29 CN claimed
CN-113292456-A Preparation method of N-fluorenylmethoxycarbonyl-L-aspartic acid-4-tert-butyl ester 常州吉恩药业有限公司 2021-08-24 CN claimed
WO-2014031204-A2 CARBOHYDRATE-SELECTIVE RECEPTORS NEW YORK UNIVERSITY (US) 2014-02-27 WO claimed
CN-102438453-A Plant growth regulator additive TAMINCO NV 2012-05-02 CN claimed
WO-2026103740-A1 CEACAM5-ANTIGEN-TARGETING ANTIBODY, ANTIBODY-DRUG CONJUGATE THEREOF AND USE THEREOF 信达生物医药科技(杭州)有限公司 2026-05-21 WO disclosed
CN-116375706-B Abamectin sodium key intermediate and preparation method thereof 时森海(杭州)医药科技有限公司 2025-02-14 CN disclosed
CN-118903456-A Ligand-drug conjugate of irinotecan analogue, preparation method and application thereof 江苏恒瑞医药股份有限公司 2024-11-08 CN disclosed
CN-118806924-A Ligand-drug conjugate of irinotecan analogue, preparation method and application thereof 江苏恒瑞医药股份有限公司 2024-10-22 CN disclosed
CN-112512591-B Ligand-drug conjugate of irinotecan analogue, preparation method and application thereof 江苏恒瑞医药股份有限公司 2024-08-16 CN disclosed
CN-118382620-A Novel compounds for degrading target proteins or polypeptides by multiple ubiquitination 普瑞泽治疗公司 2024-07-23 CN disclosed
CN-117384078-A Novel polymer, diamine compound, liquid crystal aligning agent, liquid crystal alignment film, and liquid crystal display element 日产化学株式会社 2024-01-12 CN disclosed
CN-117384077-A Novel polymer, diamine compound, liquid crystal aligning agent, liquid crystal alignment film, and liquid crystal display element 日产化学株式会社 2024-01-12 CN disclosed
EP-0641354-A4 OLIGONUCLEOTIDES HAVING AMINOHYDROCARBON PHOSPHONATE MOIETIES. PHARMAGENICS INC (US) 1996-01-10 EP disclosed
WO-1995031572-A1 AMINOHYDROCARBON PHOSPHONATE OLIGONUCLEOTIDES AND USES THEREFOR PHARMGENICS, INC. (US) 1995-11-23 WO disclosed
EP-0673388-A1 DOUBLE CHAIN PEPTIDE COMPOUNDS HAVING HEMOREGULATORY ACTIVITY NYCOMED IMAGING AS (NO) 1995-09-27 EP disclosed
EP-0643725-A1 SINGLE CHAIN PEPTIDE COMPOUNDS HAVING HEMOREGULATORY ACTIVITY NYCOMED IMAGING AS (NO) 1995-03-22 EP disclosed
EP-0641354-A1 OLIGONUCLEOTIDES HAVING AMINOHYDROCARBON PHOSPHONATE MOIETIES PHARMAGENICS, INC. (US) 1995-03-08 EP disclosed
WO-1993024524-A1 SINGLE CHAIN PEPTIDE COMPOUNDS HAVING HEMOREGULATORY ACTIVITY HAFSLUND NYCOMED AS (NO) 1993-12-09 WO disclosed
EP-0569802-A1 Arylacetamides MERCK PATENT GmbH (DE) 1993-11-18 EP disclosed
WO-1993011148-A1 OLIGONUCLEOTIDES HAVING AMINOHYDROCARBON PHOSPHONATE MOIETIES PHARMAGENICS, INC. (US) 1993-06-10 WO disclosed