Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ESR1 | P03372 | 5/20 | 0.36 |
| ▸ | ESR2 | Q92731 | 3/20 | 0.36 |
| ▸ | TMEM97 | Q5BJF2 | 2/20 | 0.34 |
| ▸ | HTR2B | P41595 | 1/20 | 0.33 |
| ▸ | SIGMAR1 | Q99720 | 1/20 | 0.33 |
| ▸ | NR1I2 | O75469 | 1/20 | 0.32 |
| ▸ | NR3C1 | P04150 | 1/20 | 0.32 |
| ▸ | PGR | P06401 | 1/20 | 0.32 |
| ▸ | ESRRA | P11474 | 1/20 | 0.32 |
| ▸ | EPHX2 | P34913 | 1/20 | 0.32 |
| ▸ | PPARG | P37231 | 1/20 | 0.32 |
| ▸ | NR1H4 | Q96RI1 | 1/20 | 0.32 |
| ▸ | SIRT5 | Q9NXA8 | 1/20 | 0.32 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.32 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.32 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.32 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7585889 | 0.87 | ESR1 (0.36) | ESR1ESR2TMEM97HTR2BSIGMAR1 | |
| SCHEMBL7588656 | 0.87 | ESR1 (0.36) | ESR1ESR2TMEM97HTR2BSIGMAR1 | |
| SCHEMBL5857401 | 0.86 | HTR2B (0.33) | TMEM97HTR2BSIGMAR1 | |
| SCHEMBL5854274 | 0.84 | L3MBTL1 (0.34) | HTR2BSIGMAR1 | |
| SCHEMBL5854576 | 0.84 | L3MBTL1 (0.34) | HTR2BSIGMAR1 | |
| SCHEMBL5856123 | 0.84 | TMEM97 (0.38) | ESR1ESR2TMEM97HTR2BSIGMAR1 | |
| SCHEMBL5854583 | 0.82 | ESR1 (0.34) | ESR1ESR2TMEM97HTR2BSIGMAR1 | |
| SCHEMBL5854227 | 0.81 | ESR1 (0.33) | ESR1ESR2TMEM97HTR2BSIGMAR1 | |
| SCHEMBL5855226 | 0.81 | ESR1 (0.47) | ESR1ESR2TMEM97HTR2BSIGMAR1 | |
| SCHEMBL5854275 | 0.81 | ESR1 (0.38) | ESR1ESR2TMEM97HTR2BSIGMAR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0944613-B1 | BENZOPYRAN DERIVATIVES | CHUGAI PHARMACEUTICAL CO LTD (JP) | 2002-10-09 | — | — | EP | disclosed |
| EP-0944613-A1 | NOVEL BENZOPYRAN DERIVATIVES | C & C Research Laboratories (KR) | 1999-09-29 | — | — | EP | disclosed |
| WO-1998025916-A1 | NOVEL BENZOPYRAN DERIVATIVES | C & C RESEARCH LABORATORIES (KR) | 1998-06-18 | — | — | WO | disclosed |