SCHEMBL7597159

SCHEMBL7597159

C#CCNc1nc2ccccc2s1

nearest known ligand 0.56

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
NPC1 O15118 12/20 0.56
RAB9A P51151 12/20 0.56
SMN1; SMN2 Q16637 8/20 0.56
IDO1 P14902 1/20 0.54
KMT2A Q03164 5/20 0.54
MEN1 O00255 4/20 0.54
HPGD P15428 1/20 0.52
MAPK1 P28482 1/20 0.52
MAPT P10636 4/20 0.51
CASP3 P42574 1/20 0.51
SENP8 Q96LD8 1/20 0.51
SENP7 Q9BQF6 1/20 0.51
SENP6 Q9GZR1 1/20 0.51
ADORA1 P30542 1/20 0.51
DYRK1A Q13627 1/20 0.51
CYP1A2 P05177 2/20 0.51
ALDH1A1 P00352 2/20 0.51
LMNA P02545 1/20 0.51
CYP3A4 P08684 1/20 0.51
CYP2D6 P10635 1/20 0.51

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL11047240 0.82 NPC1 (0.55) NPC1RAB9ASMN1; SMN2IDO1KMT2A
SCHEMBL1913774 0.81 NPC1 (0.61) NPC1RAB9ASMN1; SMN2IDO1KMT2A
SCHEMBL11016003 0.81 NPC1 (0.54) NPC1RAB9ASMN1; SMN2IDO1KMT2A
SCHEMBL1664350 0.78 NPC1 (0.67) NPC1RAB9ASMN1; SMN2IDO1KMT2A
SCHEMBL25057062 0.77 NPC1 (0.65) NPC1RAB9ASMN1; SMN2IDO1KMT2A
SCHEMBL16259088 0.77 HPGD (0.64) NPC1RAB9ASMN1; SMN2IDO1KMT2A
Hydrochloric Acid SCHEMBL2124383 0.77 NPC1 (0.65) NPC1RAB9ASMN1; SMN2IDO1KMT2A
SCHEMBL1435770 0.75 IDO1 (0.57) NPC1RAB9ASMN1; SMN2IDO1KMT2A
Hydrochloric Acid SCHEMBL7109842 0.75 NPC1 (0.63) NPC1RAB9ASMN1; SMN2IDO1KMT2A
SCHEMBL17933751 0.75 NPC1 (0.64) NPC1RAB9ASMN1; SMN2IDO1KMT2A

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 15 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-7410745-B2 Photothermographic material and image forming method using same FUJIFILM CORPORATION (JP) 2008-08-12 US disclosed
US-7309564-B2 Photothermographic material and image forming method FUJIFILM CORPORATION (JP) 2007-12-18 US disclosed
US-7303864-B2 Black and white photothermographic material and image forming method FUJIFILM CORPORATION (JP) 2007-12-04 US disclosed
EP-1818718-A2 Photothermographic material and method of thermal development of the same Fuji Photo Film Co., Ltd. (JP) 2007-08-15 EP disclosed
US-7157218-B2 Suppressed fogging and printout and is excellent in storage stability of an image against stain FUJIFILM CORPORATION (JP) 2007-01-02 US disclosed
US-7157218-B2 Suppressed fogging and printout and is excellent in storage stability of an image against stain FUJIFILM CORPORATION (JP) 2007-01-02 US disclosed
EP-0903619-B1 Silver halide photographic emulsion and silver halide light sensitive photographic material by the use thereof KONISHIROKU PHOTO IND (JP) 2002-12-11 EP disclosed
US-6489091-B2 PHOTOSENSITIVE LAYER CONTAINING ORGANIC SILVER SALT, SILVER HALIDE EMULSION AND SOLVENT ON SUPPORT KONICA CORPORATION (JP) 2002-12-03 US disclosed
US-20010041313-A1 Photothermographic material KONICA CORPORATION (JP) 2001-11-15 US disclosed
EP-1132767-A2 Photothermographic material KONICA CORPORATION (JP) 2001-09-12 EP disclosed
US-6080535-A TABULAR CORE, SHELL GRAINS KONICA CORPORATION (JP) 2000-06-27 US disclosed
EP-0903619-A2 Silver halide photographic emulsion and silver halide light sensitive photographic material by the use thereof KONICA CORPORATION (JP) 1999-03-24 EP disclosed
US-4535088-A FUNGICIDES SHIONOGI & CO., LTD. (JP) 1985-08-13 US disclosed
EP-0111904-A2 Propynylaminothiazole derivatives SHIONOGI & CO., LTD. (JP) 1984-06-27 EP disclosed
US-4451557-A Photographic speed increasing and latent image stabilizing compounds, silver halide emulsions, and photographic elements EASTMAN KODAK COMPANY (US) 1984-05-29 US disclosed