Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NPC1 | O15118 | 12/20 | 0.64 |
| ▸ | RAB9A | P51151 | 11/20 | 0.64 |
| ▸ | SMN1; SMN2 | Q16637 | 6/20 | 0.64 |
| ▸ | RIPK1 | Q13546 | 2/20 | 0.58 |
| ▸ | QPCT | Q16769 | 1/20 | 0.58 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.57 |
| ▸ | MAPT | P10636 | 3/20 | 0.57 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.57 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.57 |
| ▸ | LMNA | P02545 | 1/20 | 0.57 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.57 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.57 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.57 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.56 |
| ▸ | STAT1 | P42224 | 1/20 | 0.56 |
| ▸ | NFKB2 | Q00653 | 1/20 | 0.56 |
| ▸ | RELA | Q04206 | 1/20 | 0.56 |
| ▸ | GAA | P10253 | 1/20 | 0.54 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.54 |
| ▸ | IDO1 | P14902 | 1/20 | 0.53 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4528378 | 0.95 | NPC1 (0.61) | NPC1RAB9ASMN1; SMN2RIPK1QPCT | |
| SCHEMBL22039979 | 0.94 | NPC1 (0.60) | NPC1RAB9ASMN1; SMN2RIPK1QPCT | |
| SCHEMBL22040024 | 0.94 | NPC1 (0.60) | NPC1RAB9ASMN1; SMN2RIPK1QPCT | |
| SCHEMBL17570161 | 0.94 | NPC1 (0.60) | NPC1RAB9ASMN1; SMN2RIPK1QPCT | |
| SCHEMBL19497780 | 0.94 | NPC1 (0.60) | NPC1RAB9ASMN1; SMN2RIPK1QPCT | |
| SCHEMBL1664350 | 0.90 | NPC1 (0.67) | NPC1RAB9ASMN1; SMN2QPCTALDH1A1 | |
| Hydrochloric Acid SCHEMBL2124383 | 0.89 | NPC1 (0.65) | NPC1RAB9ASMN1; SMN2QPCTALDH1A1 | |
| Hydrochloric Acid SCHEMBL7109842 | 0.87 | NPC1 (0.63) | NPC1RAB9ASMN1; SMN2QPCTALDH1A1 | |
| SCHEMBL22040020 | 0.86 | NPC1 (0.58) | NPC1RAB9ASMN1; SMN2RIPK1QPCT | |
| SCHEMBL11074021 | 0.84 | NPC1 (0.63) | NPC1RAB9ASMN1; SMN2QPCTALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 22 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20220204497-A1 | NOVEL COMPOUND HAVING ANTICANCER ACTIVITY, AND METHOD FOR PRODUCING SAME | DONGGUK UNIVERSITY INDUSTRY-ACADEMIC COOPERATION FOUNDATION (KR) | 2022-06-30 | — | — | US | disclosed |
| US-20210228550-A1 | Inhibiting Germination of Clostridium Perfringens Spores to Reduce Necrotic Enteritis | THE BOARD OF REGENTS OF THE NEVADA SYSTEM OF HIGHER EDUCATION ON BEHALF OF THE UNIVERSITY OF NEVADA, LAS VEGAS | 2021-07-29 | — | — | US | disclosed |
| US-10945996-B2 | Inhibiting germination of clostridium perfringens spores to reduce necrotic enteritis | THE BOARD OF REGENTS OF THE NEVADA SYSTEM OF HIGHER EDUCATION ON BEHALF OF THE UNIVERSITY OF NEVADA, LAS VEGAS (US) | 2021-03-16 | — | — | US | disclosed |
| WO-2020150473-A2 | PCSK9 INHIBITORS AND METHODS OF USE THEREOF | DOGMA THERAPEUTICS, INC. (US) | 2020-07-23 | — | — | WO | disclosed |
| US-20200165215-A1 | METHOD FOR PRODUCING 2-HYDRAZINOBENZOTHIAZOLE DERIVATIVE | DIC CORPORATION (JP) | 2020-05-28 | — | — | US | disclosed |
| US-20190209531-A1 | Inhibiting Germination of Clostridium Perfringens Spores to Reduce Necrotic Enteritis | THE BOARD OF REGENTS OF THE NEVADA SYSTEM OF HIGHER EDUCATION ON BEHALF OF THE UNIVERSITY OF NEVADA, LAS VEGAS | 2019-07-11 | — | — | US | disclosed |
| WO-2019102922-A1 | POLYMERIZABLE LIQUID CRYSTAL COMPOSITION, POLYMER OF SAME, OPTICALLY ANISOTROPIC BODY, AND DISPLAY ELEMENT | DIC株式会社 | 2019-05-31 | — | — | WO | disclosed |
| WO-2018101122-A1 | POLYMERIZABLE COMPOSITION AND OPTICALLY ANISOTROPIC BODY IN WHICH SAME IS USED | DIC株式会社 | 2018-06-07 | — | — | WO | disclosed |
| US-20180031738-A1 | RETARDATION PLATE AND CIRCULARLY POLARIZING PLATE | DIC CORPORATION (JP) | 2018-02-01 | — | — | US | disclosed |
| WO-2018016567-A1 | POLYMERIZABLE COMPOSITION AND OPTICALLY ANISOTROPIC BODY USING SAME | DIC株式会社 | 2018-01-25 | — | — | WO | disclosed |
| US-20180000793-A1 | Inhibiting Germination of Clostridium Perfringens Spores to Reduce Necrotic Enteritis | ABEL-SANTOS ERNESTO (US) | 2018-01-04 | — | — | US | disclosed |
| US-20170306233-A1 | POLYMERIZABLE COMPOUND AND OPTICALLY ANISOTROPIC BODY | DIC CORPORATION (JP) | 2017-10-26 | — | — | US | disclosed |
| US-20170306233-A1 | POLYMERIZABLE COMPOUND AND OPTICALLY ANISOTROPIC BODY | DIC CORPORATION (JP) | 2017-10-26 | — | — | US | disclosed |
| WO-2017090418-A1 | POLYMERIZABLE COMPOSITION AND OPTICALLY ANISOTROPIC BODY USING SAME | DIC株式会社 | 2017-06-01 | — | — | WO | disclosed |
| WO-2016127102-A2 | INHIBITING GERMINATION OF CLOSTRIDIUM PERFRINGENS SPORES TO REDUCE NECROTIC ENTERITIS | ABEL-SANTOS ERNESTO (US) | 2016-08-11 | — | — | WO | disclosed |
| WO-2016114254-A1 | RETARDATION PLATE AND CIRCULARLY POLARIZING PLATE | DIC株式会社 | 2016-07-21 | — | — | WO | disclosed |
| WO-2016114346-A1 | POLYMERIZABLE COMPOSITION AND OPTICALLY ANISOTROPIC BODY USING SAME | DIC株式会社 | 2016-07-21 | — | — | WO | disclosed |
| WO-2016114253-A1 | POLYMERIZABLE COMPOSITION AND OPTICALLY ANISOTROPIC BODY USING SAME | DIC株式会社 | 2016-07-21 | — | — | WO | disclosed |
| CN-102321046-B | Method for preparing 2-(N-alkyl)aminothiazole and 2-(N-alkyl) aminooxazole derivative by N-alkylation reaction | UNIV NANJING SCIENCE & TECH | 2014-03-26 | — | — | CN | disclosed |
| CN-102321046-A | Method for preparing 2-(N-alkyl)aminothiazole and 2-(N-alkyl) aminooxazole derivative by N-alkylation reaction | UNIV NANJING SCIENCE & TECH | 2012-01-18 | — | — | CN | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (7 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-10945996-B2 | Inhibiting germination of clostridium perfringens spores to reduce necrotic enteritis | CASP3, SI, PYCARD | NPC1 1750/4885RAB9A 4497/4885SMN1; SMN2 4241/4885 |
| US-20200165215-A1 | METHOD FOR PRODUCING 2-HYDRAZINOBENZOTHIAZOLE DERIVATIVE | HAO2, IDH2, HACL2 | NPC1 2261/4885RAB9A 3845/4885SMN1; SMN2 4509/4885 |
| US-20170306233-A1 | POLYMERIZABLE COMPOUND AND OPTICALLY ANISOTROPIC BODY | SMC4, PHOSPHO1, SMCHD1 | NPC1 2476/4885RAB9A 4246/4885SMN1; SMN2 1598/4885 |
| US-20190209531-A1 | Inhibiting Germination of Clostridium Perfringens Spores to Reduce Necrotic Enteritis | CASP3, SI, PYCARD | NPC1 1750/4885RAB9A 4497/4885SMN1; SMN2 4241/4885 |
| US-20220204497-A1 | NOVEL COMPOUND HAVING ANTICANCER ACTIVITY, AND METHOD FOR PRODUCING SAME | TPX2, AIMP2, CDYL2 | NPC1 1722/4885RAB9A 2686/4885SMN1; SMN2 1981/4885 |
| US-20210228550-A1 | Inhibiting Germination of Clostridium Perfringens Spores to Reduce Necrotic Enteritis | CASP3, SI, PYCARD | NPC1 1750/4885RAB9A 4497/4885SMN1; SMN2 4241/4885 |
| US-20180000793-A1 | Inhibiting Germination of Clostridium Perfringens Spores to Reduce Necrotic Enteritis | CASP3, SI, PYCARD | NPC1 1750/4885RAB9A 4497/4885SMN1; SMN2 4241/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.