Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 3/20 | 0.64 |
| ▸ | THRB | P10828 | 1/20 | 0.41 |
| ▸ | POLB | P06746 | 1/20 | 0.38 |
| ▸ | APEX1 | P27695 | 1/20 | 0.38 |
| ▸ | HTT | P42858 | 1/20 | 0.38 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.38 |
| ▸ | NAAA | Q02083 | 1/20 | 0.37 |
| ▸ | ZDHHC7 | Q9NXF8 | 1/20 | 0.36 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.36 |
| ▸ | LMNA | P02545 | 1/20 | 0.36 |
| ▸ | MAPT | P10636 | 1/20 | 0.36 |
| ▸ | HCAR2 | Q8TDS4 | 1/20 | 0.36 |
| ▸ | RAD52 | P43351 | 1/20 | 0.36 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.36 |
| ▸ | FAAH | O00519 | 2/20 | 0.35 |
| ▸ | PRSS1 | P07477 | 1/20 | 0.35 |
| ▸ | PRSS2 | P07478 | 1/20 | 0.35 |
| ▸ | PRSS3 | P35030 | 1/20 | 0.35 |
| ▸ | EPHX1 | P07099 | 1/20 | 0.35 |
| ▸ | ATM | Q13315 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6684134 | 0.90 | TSHR (0.80) | TSHRTHRBPOLBAPEX1HTT | |
| SCHEMBL8169202 | 0.90 | TSHR (0.80) | TSHRTHRBPOLBAPEX1HTT | |
| SCHEMBL29140281 | 0.88 | TSHR (0.83) | TSHRTHRBPOLBAPEX1HTT | |
| SCHEMBL29199286 | 0.88 | TSHR (0.83) | TSHRTHRBPOLBAPEX1HTT | |
| SCHEMBL31403399 | 0.88 | TSHR (0.83) | TSHRTHRBPOLBAPEX1HTT | |
| SCHEMBL28384552 | 0.84 | TSHR (0.70) | TSHRTHRBPOLBAPEX1HTT | |
| SCHEMBL651325 | 0.84 | TSHR (0.75) | TSHRTHRBPOLBAPEX1HTT | |
| SCHEMBL27797297 | 0.84 | TSHR (0.65) | TSHRTHRBPOLBAPEX1HTT | |
| SCHEMBL28479741 | 0.83 | TSHR (0.62) | TSHRTHRBPOLBAPEX1HTT | |
| SCHEMBL3717075 | 0.82 | TSHR (0.72) | TSHRTHRBPOLBAPEX1HTT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1140242-B1 | POLYMER COMPOSITIONS FOR INTRALUMINAL STENT | QUANAM MEDICAL CORP (US) | 2002-10-30 | — | — | EP | claimed |