Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PTPN1 | P18031 | 2/20 | 0.39 |
| ▸ | PTPN11 | Q06124 | 1/20 | 0.39 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.34 |
| ▸ | HPGD | P15428 | 2/20 | 0.34 |
| ▸ | USP2 | O75604 | 1/20 | 0.34 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.34 |
| ▸ | WNT3A | P56704 | 1/20 | 0.32 |
| ▸ | CHRNB2 | P17787 | 3/20 | 0.32 |
| ▸ | CHRNA7 | P36544 | 3/20 | 0.32 |
| ▸ | CHRNA4 | P43681 | 3/20 | 0.32 |
| ▸ | SLC18A3 | Q16572 | 4/20 | 0.32 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.32 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.32 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.31 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.31 |
| ▸ | MEN1 | O00255 | 1/20 | 0.31 |
| ▸ | LMNA | P02545 | 1/20 | 0.31 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.31 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.31 |
| ▸ | HTT | P42858 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7117096 | 1.00 | PTPN1 (0.39) | PTPN1PTPN11KDM4EHPGDUSP2 | |
| SCHEMBL7127049 | 0.90 | KDM4E (0.46) | PTPN1PTPN11KDM4EHPGDUSP2 | |
| SCHEMBL7118038 | 0.90 | PTPN1 (0.38) | PTPN1PTPN11KDM4EHPGDUSP2 | |
| SCHEMBL7117729 | 0.89 | PTPN1 (0.42) | PTPN1PTPN11KDM4ESLC18A3ALDH1A1 | |
| SCHEMBL7115882 | 0.89 | CHRNA7 (0.38) | PTPN1PTPN11KDM4EHPGDUSP2 | |
| SCHEMBL7117126 | 0.89 | PTPN1 (0.49) | PTPN1PTPN11KDM4EHPGDUSP2 | |
| SCHEMBL7123565 | 0.89 | CHRNA7 (0.38) | PTPN1PTPN11KDM4EHPGDUSP2 | |
| SCHEMBL7595144 | 0.89 | PTPN1 (0.49) | PTPN1PTPN11KDM4EHPGDUSP2 | |
| SCHEMBL7129276 | 0.89 | PTPN1 (0.38) | PTPN1PTPN11KDM4EHPGDUSP2 | |
| SCHEMBL7130837 | 0.89 | PTPN1 (0.44) | PTPN1KDM4EHPGDUSP2HSD17B10 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2002015662-A2 | QUINUCLIDINE-SUBSTITUTED HETEROARYL MOIETIES FOR TREATMENT OF DISEASE (NICOTINIC ACETYLCHOLINE RECEPTOR ANTAGONISTS | PHARMACIA & UPJOHN COMPANY (US) | 2002-02-28 | — | — | WO | claimed |