SCHEMBL7130837

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

	Compound	similarity	top predicted	shared targets
	SCHEMBL7118038	0.90	PTPN1 (0.38)	PTPN1ALDH1A1L3MBTL1HTTKDM4E
	SCHEMBL7127049	0.90	KDM4E (0.46)	PTPN1ALDH1A1L3MBTL1HTTKDM4E
	SCHEMBL7129276	0.89	PTPN1 (0.38)	PTPN1ALDH1A1L3MBTL1HTTKDM4E
	SCHEMBL7223878	0.89	CHRNA7 (0.42)	PTPN1ALDH1A1HTTKDM4ELMNA
	SCHEMBL7115882	0.89	CHRNA7 (0.38)	PTPN1ALDH1A1HTTKDM4ELMNA
	SCHEMBL7123565	0.89	CHRNA7 (0.38)	PTPN1L3MBTL1KDM4EHPGDKMT2A
	SCHEMBL7117126	0.89	PTPN1 (0.49)	PTPN1ALDH1A1HTTKDM4ELMNA
	SCHEMBL7117096	0.89	PTPN1 (0.39)	PTPN1ALDH1A1L3MBTL1HTTKDM4E
	SCHEMBL7597272	0.89	PTPN1 (0.39)	PTPN1ALDH1A1L3MBTL1HTTKDM4E
	SCHEMBL7595144	0.89	PTPN1 (0.49)	PTPN1ALDH1A1HTTKDM4ELMNA

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 20 patents. claimed = in the patent's claims; disclosed = body only.

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.