Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 3/20 | 0.40 |
| ▸ | NPC1 | O15118 | 1/20 | 0.39 |
| ▸ | RAB9A | P51151 | 1/20 | 0.39 |
| ▸ | SYK | P43405 | 1/20 | 0.36 |
| ▸ | CTSL | P07711 | 3/20 | 0.35 |
| ▸ | CTSB | P07858 | 2/20 | 0.35 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.35 |
| ▸ | HDAC3 | O15379 | 1/20 | 0.35 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.35 |
| ▸ | HDAC2 | Q92769 | 1/20 | 0.35 |
| ▸ | KCNQ3 | O43525 | 2/20 | 0.34 |
| ▸ | KCNQ2 | O43526 | 2/20 | 0.34 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.34 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.34 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.34 |
| ▸ | MEN1 | O00255 | 1/20 | 0.34 |
| ▸ | APAF1 | O14727 | 1/20 | 0.34 |
| ▸ | GMNN | O75496 | 1/20 | 0.34 |
| ▸ | USP2 | O75604 | 1/20 | 0.34 |
| ▸ | G6PD | P11413 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7399366 | 0.82 | MAPT (0.41) | MAPTNPC1RAB9ASYKSMN1; SMN2 | |
| SCHEMBL7399365 | 0.82 | MAPT (0.41) | MAPTNPC1RAB9ASYKSMN1; SMN2 | |
| SCHEMBL7401757 | 0.77 | MAPT (0.45) | MAPTNPC1RAB9ASMN1; SMN2ALDH1A1 | |
| SCHEMBL7401754 | 0.77 | MAPT (0.45) | MAPTNPC1RAB9ASMN1; SMN2ALDH1A1 | |
| SCHEMBL8889937 | 0.72 | NPC1 (0.45) | MAPTNPC1RAB9ASYKSMN1; SMN2 | |
| SCHEMBL19346024 | 0.68 | LMNA (0.55) | MAPTNPC1RAB9ACTSLCTSB | |
| SCHEMBL7402954 | 0.68 | NPC1 (0.45) | MAPTNPC1RAB9ASYKSMN1; SMN2 | |
| SCHEMBL7398862 | 0.67 | MAPT (0.47) | MAPTNPC1RAB9ASMN1; SMN2KMT2A | |
| SCHEMBL7398861 | 0.67 | MAPT (0.47) | MAPTNPC1RAB9ASMN1; SMN2KMT2A | |
| SCHEMBL13737363 | 0.67 | NPC1 (0.49) | NPC1RAB9ASYKSMN1; SMN2HDAC3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0593603-B1 | BICYCLIC FIBRINOGEN ANTAGONISTS | SMITHKLINE BEECHAM CORP (US) | 2002-11-20 | — | — | EP | disclosed |