Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.65 |
| ▸ | KDM4E | B2RXH2 | 4/20 | 0.65 |
| ▸ | MEN1 | O00255 | 1/20 | 0.58 |
| ▸ | POLB | P06746 | 1/20 | 0.58 |
| ▸ | PABPC1 | P11940 | 1/20 | 0.58 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.58 |
| ▸ | LMNA | P02545 | 2/20 | 0.50 |
| ▸ | NPC1 | O15118 | 1/20 | 0.50 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.50 |
| ▸ | RECQL | P46063 | 1/20 | 0.49 |
| ▸ | HTT | P42858 | 1/20 | 0.48 |
| ▸ | CA12 | O43570 | 1/20 | 0.47 |
| ▸ | CA1 | P00915 | 1/20 | 0.47 |
| ▸ | CA2 | P00918 | 1/20 | 0.47 |
| ▸ | CA7 | P43166 | 1/20 | 0.47 |
| ▸ | CA9 | Q16790 | 1/20 | 0.47 |
| ▸ | CA14 | Q9ULX7 | 1/20 | 0.47 |
| ▸ | CFTR | P13569 | 2/20 | 0.44 |
| ▸ | TSHR | P16473 | 1/20 | 0.44 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7598991 | 0.87 | ALDH1A1 (0.68) | ALDH1A1KDM4EMEN1POLBPABPC1 | |
| SCHEMBL10044901 | 0.86 | ALDH1A1 (0.67) | ALDH1A1KDM4EMEN1POLBPABPC1 | |
| SCHEMBL1685962 | 0.85 | ALDH1A1 (0.65) | ALDH1A1KDM4EMEN1POLBPABPC1 | |
| SCHEMBL6997297 | 0.84 | KDM4E (0.61) | ALDH1A1KDM4EMEN1POLBPABPC1 | |
| SCHEMBL6996658 | 0.84 | ALDH1A1 (0.64) | ALDH1A1KDM4EMEN1POLBPABPC1 | |
| SCHEMBL5165226 | 0.83 | ALDH1A1 (0.62) | ALDH1A1KDM4EMEN1POLBPABPC1 | |
| SCHEMBL7617278 | 0.83 | ALDH1A1 (0.62) | ALDH1A1KDM4EMEN1POLBPABPC1 | |
| SCHEMBL7614893 | 0.83 | ALDH1A1 (0.62) | ALDH1A1KDM4EMEN1POLBPABPC1 | |
| SCHEMBL6994140 | 0.82 | KDM4E (0.59) | ALDH1A1KDM4EMEN1POLBPABPC1 | |
| SCHEMBL7617273 | 0.82 | ALDH1A1 (0.61) | ALDH1A1KDM4EMEN1POLBPABPC1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1073639-B1 | QUINOLINE DERIVATIVES | ACTIVE BIOTECH AB (SE) | 2002-11-27 | — | — | EP | disclosed |
| US-6077851-A | USED FOR TREATMENT OF DISEASES RESULTING FROM AUTOIMMUNITY SUCH AS MULTIPLE SCLEROSIS, INSULIN-DEPENDENT DIABETES MELLITUS, SYSTEMIC LUPUS ERYTHEMATOSUS, RHEUMATOID ARTHRITIS, INFAMMATORY BOWEL DISEASE AND PSORIASIS; LAQUINIMOD AS NEW CHEMICAL ENTITY | ACTIVE BIOTECH AB (SE) | 2000-06-20 | — | — | US | disclosed |