SCHEMBL7597896

SCHEMBL7597896

CCC(=O)NCC1CN(c2ccc3c(c2)CC(C)N3C=O)C(=O)O1

nearest known ligand 0.49

Predicted protein targets (top 7)

geneUniProtsupporting neighboursconfidence
MAOB P27338 4/20 0.49
MAOA P21397 3/20 0.49
LMNA P02545 1/20 0.49
PTGS1 P23219 1/20 0.49
CALML3 P27482 1/20 0.49
SDHA P31040 1/20 0.49
F10 P00742 15/20 0.45

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL6040537 1.00 MAOB (0.49) MAOBMAOALMNAPTGS1CALML3
SCHEMBL6040518 0.91 MAOA (0.59) MAOBMAOALMNAPTGS1CALML3
SCHEMBL6040829 0.88 MAOB (0.52) MAOBMAOALMNAPTGS1CALML3
SCHEMBL6966689 0.86 MAOB (0.49) MAOBMAOALMNAPTGS1CALML3
SCHEMBL6040386 0.82 MAOA (0.56) MAOBMAOALMNAPTGS1CALML3
SCHEMBL6968441 0.82 MAOA (0.56) MAOBMAOALMNAPTGS1CALML3
SCHEMBL8131704 0.80 F10 (0.55) MAOBMAOALMNAPTGS1CALML3
SCHEMBL6958923 0.80 MAOA (0.58) MAOBMAOALMNAPTGS1CALML3
SCHEMBL6040470 0.80 MAOB (0.49) MAOBMAOALMNAPTGS1CALML3
SCHEMBL6958928 0.80 MAOA (0.58) MAOBMAOALMNAPTGS1CALML3

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-1181288-A1 BICYCLIC OXAZOLIDINONES AS ANTIBACTERIAL AGENT PHARMACIA & UPJOHN COMPANY (US) 2002-02-27 EP disclosed
WO-2000073301-A1 BICYCLIC OXAZOLIDINONES AS ANTIBACTERIAL AGENT PHARMACIA & UPJOHN COMPANY (US) 2000-12-07 WO disclosed