Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.39 |
| ▸ | MEN1 | O00255 | 1/20 | 0.38 |
| ▸ | POLB | P06746 | 1/20 | 0.38 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.38 |
| ▸ | TSHR | P16473 | 1/20 | 0.32 |
| ▸ | BLM | P54132 | 1/20 | 0.31 |
| ▸ | PMP22 | Q01453 | 1/20 | 0.31 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.31 |
| ▸ | HRH3 | Q9Y5N1 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL749829 | 0.91 | ALDH1A1 (0.45) | ALDH1A1MEN1POLBKMT2ATSHR | |
| SCHEMBL16592400 | 0.91 | MEN1 (0.33) | ALDH1A1MEN1POLBKMT2A | |
| SCHEMBL27361642 | 0.91 | HTR1B (0.38) | MEN1POLBKMT2A | |
| SCHEMBL19144434 | 0.90 | MEN1 (0.45) | ALDH1A1MEN1POLBKMT2ATSHR | |
| SCHEMBL9705211 | 0.88 | MEN1 (0.41) | ALDH1A1MEN1POLBKMT2ATSHR | |
| SCHEMBL9705218 | 0.88 | MEN1 (0.41) | ALDH1A1MEN1POLBKMT2ATSHR | |
| SCHEMBL9705659 | 0.88 | MEN1 (0.41) | ALDH1A1MEN1POLBKMT2ATSHR | |
| SCHEMBL9705246 | 0.86 | BLM (0.42) | MEN1POLBKMT2ATSHRBLM | |
| SCHEMBL1323791 | 0.86 | BLM (0.42) | ALDH1A1MEN1POLBKMT2ATSHR | |
| SCHEMBL9136240 | 0.86 | BLM (0.42) | ALDH1A1MEN1POLBKMT2ATSHR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-100338046-C | Antimalarial and anti-babesiosis agent and pharmaceutical compositions contg. same | VIRBAC SA (FR) | 2007-09-19 | — | — | CN | disclosed |
| EP-0917465-B1 | ANTIMALARIAL AND ANTI-BABESIOSIS AGENTS AND PHARMACEUTICAL COMPOSITIONS CONTAINING THE SAME AGENTS | VIRBAC SA (FR) | 2002-11-20 | — | — | EP | disclosed |
| US-6096788-A | MOLECULES CONTAINING TWO QUATERNARY AMMONIUM GROUPS ON ENDS OF HYDROCARBON CHAIN | VIRBAC S.A. (FR) | 2000-08-01 | — | — | US | disclosed |
| CN-1232388-A | Antimalarial and babesiosis-resistant agents and pharmaceutical compositions containing them | VIRBAC SA (FR) | 1999-10-20 | — | — | CN | disclosed |
| EP-0917465-A1 | ANTIMALARIAL AND ANTI-BABESIOSIS AGENTS AND PHARMACEUTICAL COMPOSITIONS CONTAINING SAME | Virbac S.A. (FR) | 1999-05-26 | — | — | EP | disclosed |
| WO-1998004252-A1 | ANTIMALARIAL AND ANTI-BABESIOSIS AGENTS AND PHARMACEUTICAL COMPOSITIONS CONTAINING SAME | VIRBAC S.A. (FR) | 1998-02-05 | — | — | WO | disclosed |