SCHEMBL7598038

SCHEMBL7598038

CCCCC1CCC(C)C1[Si](Cl)(Cl)Cl

nearest known ligand 0.33

Predicted protein targets (top 5)

geneUniProtsupporting neighboursconfidence
CYP1A2 P05177 1/20 0.33
NOS3 P29474 1/20 0.33
NOS1 P29475 1/20 0.33
NOS2 P35228 1/20 0.33
DPP4 P27487 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL7598163 0.89 CYP1A2 (0.35) CYP1A2NOS3NOS1NOS2DPP4
SCHEMBL7593041 0.88 NOS1 (0.33) NOS1NOS2
SCHEMBL7594620 0.88 CYP1A2 (0.38) CYP1A2NOS1NOS2DPP4
SCHEMBL7599113 0.80 CYP1A2 (0.40) CYP1A2NOS1NOS2DPP4
SCHEMBL7597138 0.79
SCHEMBL7593982 0.79 CYP1A2 (0.32) CYP1A2NOS1NOS2
SCHEMBL7598354 0.77 CA1 (0.39) NOS1NOS2
SCHEMBL7597043 0.76 CYP1A2 (0.36) CYP1A2NOS1NOS2DPP4
Water SCHEMBL10632009 0.74 CYP1A2 (0.41) CYP1A2NOS3NOS1NOS2DPP4
SCHEMBL7595030 0.74 CA1 (0.38) NOS1NOS2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-0894802-B1 Silane compound NIPPON MITSUBISHI OIL CORP (JP) 2002-11-06 EP disclosed
US-6150549-A Silane compound NIPPON MITSUBISHI OIL CORPORATION (JP) 2000-11-21 US disclosed
EP-0894802-A2 Silane compound NIPPON OIL CO. LTD. (JP) 1999-02-03 EP disclosed