Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.67 |
| ▸ | POLB | P06746 | 3/20 | 0.61 |
| ▸ | LMNA | P02545 | 2/20 | 0.61 |
| ▸ | USP2 | O75604 | 1/20 | 0.61 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.51 |
| ▸ | PKM | P14618 | 2/20 | 0.49 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.49 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.49 |
| ▸ | MEN1 | O00255 | 1/20 | 0.48 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.48 |
| ▸ | NPC1 | O15118 | 3/20 | 0.47 |
| ▸ | RAB9A | P51151 | 2/20 | 0.47 |
| ▸ | MAPT | P10636 | 2/20 | 0.46 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.44 |
| ▸ | MCL1 | Q07820 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7592787 | 0.86 | ALDH1A1 (0.71) | ALDH1A1POLBLMNAUSP2KDM4E | |
| SCHEMBL7590968 | 0.83 | ALDH1A1 (0.63) | ALDH1A1POLBLMNAUSP2KDM4E | |
| SCHEMBL6909436 | 0.83 | ALDH1A1 (0.68) | ALDH1A1POLBLMNAUSP2KDM4E | |
| SCHEMBL4703081 | 0.83 | ALDH1A1 (0.68) | ALDH1A1POLBLMNAUSP2KDM4E | |
| SCHEMBL6907958 | 0.83 | ALDH1A1 (0.68) | ALDH1A1POLBLMNAUSP2KDM4E | |
| SCHEMBL7590574 | 0.81 | ALDH1A1 (0.67) | ALDH1A1POLBLMNAUSP2KDM4E | |
| SCHEMBL7599667 | 0.81 | ALDH1A1 (0.67) | ALDH1A1POLBLMNAUSP2KDM4E | |
| SCHEMBL18304685 | 0.80 | NPC1 (0.54) | ALDH1A1POLBMEN1KMT2ANPC1 | |
| SCHEMBL31205637 | 0.80 | NPC1 (0.54) | ALDH1A1POLBMEN1KMT2ANPC1 | |
| SCHEMBL7594363 | 0.79 | ALDH1A1 (0.54) | ALDH1A1POLBLMNAUSP2KDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6384265-B1 | ACID CATALYSIS FOR REARRANGEMENT/INVERSION OF STEREOCONFIGURATION; KINETIC RESOLUTION OF RACEMIC MIXTURES USING A CHIRAL CATALYST | COLORADO STATE UNIVERSITY RESEARCH FOUNDATION | 2002-05-07 | — | — | US | disclosed |
| EP-1169291-A1 | METHODS FOR PRODUCING $g(a)-ACYLOXY CARBONYL COMPOUNDS FROM ENOL ESTER EPOXIDES | COLORADO STATE UNIVERSITY RESEARCH FOUNDATION (US) | 2002-01-09 | — | — | EP | disclosed |
| WO-2000056696-A1 | METHODS FOR PRODUCING α-ACYLOXY CARBONYL COMPOUNDS FROM ENOL ESTER EPOXIDES | COLORADO STATE UNIVERSITY RESEARCH FOUNDATION (US) | 2000-09-28 | — | — | WO | disclosed |