Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 7/20 | 0.72 |
| ▸ | KMT2A | Q03164 | 6/20 | 0.72 |
| ▸ | MAPK1 | P28482 | 5/20 | 0.72 |
| ▸ | CYP3A4 | P08684 | 5/20 | 0.72 |
| ▸ | MEN1 | O00255 | 5/20 | 0.72 |
| ▸ | KDM4E | B2RXH2 | 5/20 | 0.72 |
| ▸ | HSD17B10 | Q99714 | 4/20 | 0.72 |
| ▸ | HPGD | P15428 | 4/20 | 0.72 |
| ▸ | TDP1 | Q9NUW8 | 4/20 | 0.72 |
| ▸ | ALOX15 | P16050 | 3/20 | 0.72 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.72 |
| ▸ | THRB | P10828 | 2/20 | 0.72 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.72 |
| ▸ | CYP2C19 | P33261 | 3/20 | 0.66 |
| ▸ | BCHE | P06276 | 1/20 | 0.66 |
| ▸ | LMNA | P02545 | 3/20 | 0.63 |
| ▸ | ABCG2 | Q9UNQ0 | 2/20 | 0.63 |
| ▸ | NPC1 | O15118 | 1/20 | 0.63 |
| ▸ | RECQL | P46063 | 1/20 | 0.63 |
| ▸ | RAB9A | P51151 | 1/20 | 0.63 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL25212453 | 1.00 | MAPT (0.72) | MAPTKMT2AMAPK1CYP3A4MEN1 | |
| SCHEMBL31233200 | 1.00 | MAPT (0.72) | MAPTKMT2AMAPK1CYP3A4MEN1 | |
| SCHEMBL30383956 | 0.90 | MAOA (0.69) | MAPTKMT2AMAPK1CYP3A4MEN1 | |
| SCHEMBL25195813 | 0.90 | MAOA (0.69) | MAPTKMT2AMAPK1CYP3A4MEN1 | |
| SCHEMBL16670790 | 0.90 | MAOA (0.69) | MAPTKMT2AMAPK1CYP3A4MEN1 | |
| SCHEMBL30383805 | 0.89 | MAPT (0.77) | MAPTKMT2AMAPK1CYP3A4MEN1 | |
| SCHEMBL11586243 | 0.89 | MAPT (0.77) | MAPTKMT2AMAPK1CYP3A4MEN1 | |
| SCHEMBL6289491 | 0.88 | GUSB (0.72) | MAPTKMT2AMAPK1CYP3A4MEN1 | |
| SCHEMBL6289490 | 0.88 | GUSB (0.72) | MAPTKMT2AMAPK1CYP3A4MEN1 | |
| SCHEMBL25188827 | 0.86 | CYP3A4 (0.84) | MAPTKMT2AMAPK1CYP3A4MEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1263454-A2 | METHODS FOR ENHANCING THE BIOAVAILABILITY OF A DRUG | Praecis Pharmaceuticals Incorporated (US) | 2002-12-11 | — | — | EP | disclosed |
| WO-2001058470-A2 | METHODS FOR ENHANCING THE BIOAVAILABILITY OF A DRUG | PRAECIS PHARMACEUTICALS INCORPORATED (US) | 2001-08-16 | — | — | WO | disclosed |