Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.38 |
| ▸ | MAPT | P10636 | 1/20 | 0.38 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.36 |
| ▸ | HPGD | P15428 | 2/20 | 0.36 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.36 |
| ▸ | TP53 | P04637 | 1/20 | 0.35 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.35 |
| ▸ | TSHR | P16473 | 1/20 | 0.35 |
| ▸ | CDC25B | P30305 | 1/20 | 0.35 |
| ▸ | ATM | Q13315 | 1/20 | 0.35 |
| ▸ | KDM1A | O60341 | 1/20 | 0.34 |
| ▸ | RAB9A | P51151 | 2/20 | 0.33 |
| ▸ | PPARG | P37231 | 8/20 | 0.33 |
| ▸ | PPARA | Q07869 | 8/20 | 0.33 |
| ▸ | MCL1 | Q07820 | 1/20 | 0.32 |
| ▸ | ACMSD | Q8TDX5 | 1/20 | 0.32 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.31 |
| ▸ | ACP1 | P24666 | 1/20 | 0.31 |
| ▸ | HDAC8 | Q9BY41 | 1/20 | 0.30 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29385153 | 0.84 | ALDH1A1 (0.50) | ALDH1A1MAPTCYP3A4HPGDHSD17B10 | |
| SCHEMBL349530 | 0.84 | ALDH1A1 (0.50) | ALDH1A1MAPTCYP3A4HPGDHSD17B10 | |
| SCHEMBL21699686 | 0.84 | ALDH1A1 (0.42) | ALDH1A1MAPTCYP3A4HPGDHSD17B10 | |
| SCHEMBL75980 | 0.81 | ALDH1A1 (0.45) | ALDH1A1MAPTCYP3A4HPGDHSD17B10 | |
| SCHEMBL13175115 | 0.81 | ALDH1A1 (0.54) | ALDH1A1MAPTCYP3A4HPGDHSD17B10 | |
| SCHEMBL557047 | 0.80 | ALDH1A1 (0.35) | ALDH1A1CYP3A4HPGDHSD17B10TP53 | |
| SCHEMBL7716912 | 0.80 | MEN1 (0.36) | ALDH1A1MAPTCYP3A4HPGDHSD17B10 | |
| SCHEMBL12956003 | 0.79 | ALDH1A1 (0.58) | ALDH1A1MAPTCYP3A4HPGDHSD17B10 | |
| SCHEMBL29404719 | 0.79 | ALDH1A1 (0.49) | ALDH1A1MAPTCYP3A4HPGDHSD17B10 | |
| SCHEMBL19738510 | 0.79 | ALDH1A1 (0.45) | ALDH1A1MAPTCYP3A4HPGDHSD17B10 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-8129039-B2 | Phosphorescent OLED device with certain fluoranthene host | GLOBAL OLED TECHNOLOGY, LLC (US) | 2012-03-06 | — | — | US | disclosed |
| US-20090108736-A1 | PHOSPHORESCENT OLED DEVICE WITH CERTAIN FLUORANTHENE HOST | GLOBAL OLED TECHNOLOGY LLC | 2009-04-30 | — | — | US | disclosed |