Di(Hydroxyethyl)Ether

Di(Hydroxyethyl)Ether

SCHEMBL7598168

OCCCO.OCCOCCO

nearest known ligand 0.77

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Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
TSHR P16473 3/20 0.77
MAPK1 P28482 2/20 0.77
MEN1 O00255 4/20 0.71
KMT2A Q03164 4/20 0.71
ALDH1A1 P00352 4/20 0.50
THRB P10828 1/20 0.50
HTT P42858 1/20 0.50
MAPT P10636 1/20 0.50
GAA P10253 1/20 0.34
SMN1; SMN2 Q16637 2/20 0.32
LMNA P02545 2/20 0.31
USP2 O75604 1/20 0.31
CYP3A4 P08684 1/20 0.31
CASP1 P29466 1/20 0.31
SLCO1B3 Q9NPD5 1/20 0.31
SLCO1B1 Q9Y6L6 1/20 0.31
APP P05067 1/20 0.30
CYP4F2 P78329 1/20 0.30
CYP4A11 Q02928 1/20 0.30
HSD17B10 Q99714 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Triethylene Glycol SCHEMBL22685883 0.96 MEN1 (0.79) TSHRMAPK1MEN1KMT2AALDH1A1
Tetraethylene Glycol SCHEMBL16245397 0.96 MEN1 (0.79) TSHRMAPK1MEN1KMT2AALDH1A1
Di(Hydroxyethyl)Ether SCHEMBL1686010 0.92 TSHR (0.77) TSHRMAPK1MEN1KMT2AALDH1A1
1,5-Pentanediol SCHEMBL11430206 0.89 TSHR (0.71) TSHRMAPK1MEN1KMT2AALDH1A1
Triethylene Glycol SCHEMBL10907018 0.89 MEN1 (0.79) TSHRMAPK1MEN1KMT2AALDH1A1
1,6-Hexanediol SCHEMBL270712 0.89 TSHR (0.71) TSHRMAPK1MEN1KMT2AALDH1A1
Di(Hydroxyethyl)Ether SCHEMBL4816588 0.89 TSHR (0.71) TSHRMAPK1MEN1KMT2AALDH1A1
Triethylene Glycol SCHEMBL3066155 0.89 MEN1 (0.79) TSHRMAPK1MEN1KMT2AALDH1A1
SCHEMBL168645 0.89
Tetraethylene Glycol SCHEMBL2590115 0.89 MEN1 (0.79) TSHRMAPK1MEN1KMT2AALDH1A1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-110023422-A Ink composition, writing instrument, and method for producing ink composition 派通株式会社 2019-07-16 CN disclosed
CN-104685043-B External structuring system for liquid laundry detergent compositions 宝洁公司 2018-07-06 CN disclosed
US-6447973-B1 COMPRISING A CARRIER LIQUID OF SILICON OIL, TONER PARTICLES, AND AN ERUCAMIDE COMPOUND TO PREVENT TONER FROM DEPOSITING ON THE FIXATION ROLLER RICOH COMPANY, LTD. (JP) 2002-09-10 US disclosed
US-6331577-B1 Process for producing elastic polyurethane moldings with compact surfaces and cellular cores BASF AKTIENGESELLSCHAFT (DE) 2001-12-18 US disclosed
US-4581387-A REACTION PRODUCT OF MONTANIC ACID AND TEN OR MORE CARBON ATOMS CARBOXYLIC ACID AND POLYOL, ALKANOLAMINE, OR POLYAMINE BASF AKTIENGESELLSCHAFT (DE) 1986-04-08 US disclosed
US-4138376-A Coating compositions IMPERIAL CHEMICAL INDUSTRIES LIMITED (GB) 1979-02-06 US disclosed