SCHEMBL7598237

SCHEMBL7598237

C[Si](C)(C)CCOCOc1cc(COC2CNCCC2c2ccc(F)cc2)cc2ccccc12

nearest known ligand 0.51

Predicted protein targets (top 1)

geneUniProtsupporting neighboursconfidence
REN P00797 20/20 0.51

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Bicarbonate SCHEMBL7553911 0.96 REN (0.50) REN
SCHEMBL6042623 0.95 REN (0.53) REN
SCHEMBL7564593 0.92 REN (0.51) REN
SCHEMBL7552004 0.92 REN (0.53) REN
SCHEMBL7554113 0.91 REN (0.50) REN
SCHEMBL7545933 0.90 REN (0.55) REN
SCHEMBL7546888 0.88 REN (0.68) REN
SCHEMBL7546952 0.88 REN (0.51) REN
SCHEMBL7540900 0.86 REN (0.60) REN
SCHEMBL6043005 0.85 REN (0.58) REN

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
WO-2002076440-A2 METHODS OF TREATING ALZHEIMER'S DISEASE WITH PIPERIDIN DERIVATES ELAN PHARMACEUTICALS, INC. (US) 2002-10-03 WO disclosed