⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7592242 | 0.92 | MEN1 (0.30) | — | |
| SCHEMBL7596579 | 0.90 | — | — | |
| SCHEMBL7597510 | 0.90 | — | — | |
| SCHEMBL8793093 | 0.64 | EPHX1 (0.31) | — | |
| SCHEMBL6216213 | 0.61 | — | — | |
| SCHEMBL11560311 | 0.60 | TSHR (0.38) | — | |
| SCHEMBL11507498 | 0.60 | — | — | |
| SCHEMBL9918184 | 0.58 | SHBG (0.33) | — | |
| SCHEMBL21244506 | 0.56 | EPHX1 (0.39) | — | |
| SCHEMBL25237437 | 0.54 | EPHX1 (0.31) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0663394-B1 | Process for preparing 5-aminodihydropyrrole, intermediate thereof and process for preparing said intermediate | SUMITOMO CHEMICAL CO (JP) | 2002-11-13 | — | — | EP | disclosed |
| US-5498725-A | Process for preparing 5-aminodihydropyrrole intermediate thereof and process for preparing said intermediate | SUMITOMO CHEMICAL COMPANY, LIMITED (JP) | 1996-03-12 | — | — | US | disclosed |
| EP-0663394-A1 | Process for preparing 5-aminodihydropyrrole, intermediate thereof and process for preparing said intermediate | SUMITOMO CHEMICAL COMPANY, LIMITED (JP) | 1995-07-19 | — | — | EP | disclosed |