Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | FOLH1 | Q04609 | 6/20 | 0.47 |
| ▸ | HTT | P42858 | 1/20 | 0.45 |
| ▸ | SLC1A3 | P43003 | 1/20 | 0.44 |
| ▸ | SLC1A1 | P43005 | 1/20 | 0.44 |
| ▸ | MEN1 | O00255 | 1/20 | 0.42 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.42 |
| ▸ | SIRT2 | Q8IXJ6 | 1/20 | 0.42 |
| ▸ | DPP8 | Q6V1X1 | 1/20 | 0.41 |
| ▸ | DPP7 | Q9UHL4 | 1/20 | 0.41 |
| ▸ | LMNA | P02545 | 1/20 | 0.41 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.41 |
| ▸ | TGM2 | P21980 | 1/20 | 0.41 |
| ▸ | KEAP1 | Q14145 | 2/20 | 0.41 |
| ▸ | NFE2L2 | Q16236 | 2/20 | 0.41 |
| ▸ | OPRK1 | P41145 | 1/20 | 0.40 |
| ▸ | ANPEP | P15144 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7598858 | 0.91 | FOLH1 (0.46) | FOLH1HTTSLC1A3SLC1A1DPP8 | |
| SCHEMBL7600933 | 0.91 | FOLH1 (0.46) | FOLH1HTTSLC1A3SLC1A1DPP8 | |
| SCHEMBL7597839 | 0.89 | FOLH1 (0.49) | FOLH1HTTSLC1A3SLC1A1DPP8 | |
| SCHEMBL7595812 | 0.89 | FOLH1 (0.49) | FOLH1HTTSLC1A3SLC1A1DPP8 | |
| SCHEMBL7600627 | 0.87 | MAPT (0.47) | FOLH1HTTSLC1A3SLC1A1MEN1 | |
| SCHEMBL7595801 | 0.87 | FOLH1 (0.43) | FOLH1HTTSLC1A3SLC1A1DPP8 | |
| SCHEMBL7600358 | 0.87 | FOLH1 (0.43) | FOLH1HTTSLC1A3SLC1A1DPP8 | |
| SCHEMBL7597117 | 0.86 | FOLH1 (0.46) | FOLH1HTTSLC1A3SLC1A1DPP8 | |
| SCHEMBL7595116 | 0.86 | FOLH1 (0.46) | FOLH1HTTSLC1A3SLC1A1DPP8 | |
| SCHEMBL7601605 | 0.85 | FOLH1 (0.47) | FOLH1HTTSLC1A3SLC1A1SIRT2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1017672-B1 | NEW NPY ANTAGONISTS | ASTRAZENECA AB (SE) | 2002-11-27 | — | — | EP | disclosed |