Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | FOLH1 | Q04609 | 5/20 | 0.47 |
| ▸ | MMP2 | P08253 | 5/20 | 0.46 |
| ▸ | MMP9 | P14780 | 5/20 | 0.46 |
| ▸ | MMP3 | P08254 | 3/20 | 0.45 |
| ▸ | MMP14 | P50281 | 2/20 | 0.45 |
| ▸ | MMP1 | P03956 | 2/20 | 0.45 |
| ▸ | MMP7 | P09237 | 2/20 | 0.45 |
| ▸ | HTT | P42858 | 1/20 | 0.43 |
| ▸ | MMP13 | P45452 | 1/20 | 0.43 |
| ▸ | SLC1A3 | P43003 | 1/20 | 0.42 |
| ▸ | SLC1A1 | P43005 | 1/20 | 0.42 |
| ▸ | CPB1 | P15086 | 1/20 | 0.42 |
| ▸ | CPB2 | Q96IY4 | 1/20 | 0.42 |
| ▸ | SIRT2 | Q8IXJ6 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7595812 | 0.95 | FOLH1 (0.49) | FOLH1HTTSLC1A3SLC1A1CPB1 | |
| SCHEMBL7597839 | 0.95 | FOLH1 (0.49) | FOLH1HTTSLC1A3SLC1A1CPB1 | |
| SCHEMBL7597117 | 0.94 | FOLH1 (0.46) | FOLH1HTTSLC1A3SLC1A1CPB1 | |
| SCHEMBL7595116 | 0.94 | FOLH1 (0.46) | FOLH1HTTSLC1A3SLC1A1CPB1 | |
| SCHEMBL7600868 | 0.92 | FOLH1 (0.45) | FOLH1HTTSLC1A3SLC1A1 | |
| SCHEMBL7600359 | 0.92 | FOLH1 (0.45) | FOLH1MMP2MMP9MMP3MMP1 | |
| SCHEMBL7600231 | 0.92 | FOLH1 (0.45) | FOLH1MMP2MMP9MMP3MMP1 | |
| SCHEMBL7597929 | 0.91 | CA1 (0.45) | FOLH1HTTSLC1A3SLC1A1 | |
| SCHEMBL7600355 | 0.91 | CA1 (0.45) | FOLH1HTTSLC1A3SLC1A1 | |
| SCHEMBL7600672 | 0.91 | FOLH1 (0.44) | FOLH1HTTSLC1A3SLC1A1CPB1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1017672-B1 | NEW NPY ANTAGONISTS | ASTRAZENECA AB (SE) | 2002-11-27 | — | — | EP | disclosed |