SCHEMBL7598684

SCHEMBL7598684

c1ccc(Oc2ccccc2C2CCCCC2)cc1

nearest known ligand 0.70

Predicted protein targets (top 15)

geneUniProtsupporting neighboursconfidence
HTR1A P08908 8/20 0.70
SLC6A2 P23975 8/20 0.70
SLC6A4 P31645 8/20 0.70
SLC6A3 Q01959 8/20 0.70
PTGDR2 Q9Y5Y4 1/20 0.55
KDM1A O60341 2/20 0.54
HTR1D P28221 2/20 0.43
HTR1B P28222 2/20 0.43
PKM P14618 1/20 0.43
ADRA2A P08913 1/20 0.43
ADRA2B P18089 1/20 0.43
ADRA2C P18825 1/20 0.43
HTR2C P28335 2/20 0.42
MEN1 O00255 1/20 0.41
KMT2A Q03164 1/20 0.41

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL2399633 0.88 PTGDR2 (0.57) HTR1ASLC6A2SLC6A4SLC6A3PTGDR2
SCHEMBL11169464 0.86 SLC6A2 (0.54) HTR1ASLC6A2SLC6A4SLC6A3PTGDR2
SCHEMBL555108 0.86 HTR1A (0.54) HTR1ASLC6A2SLC6A4SLC6A3PTGDR2
SCHEMBL11190567 0.86 HTR1A (0.54) HTR1ASLC6A2SLC6A4SLC6A3PTGDR2
SCHEMBL34461993 0.85 PTGDR2 (0.56) HTR1ASLC6A2SLC6A4SLC6A3PTGDR2
SCHEMBL4699769 0.82 SLC6A2 (1.00) HTR1ASLC6A2SLC6A4SLC6A3KDM1A
SCHEMBL2352902 0.81 PTGDR2 (0.58) HTR1ASLC6A2SLC6A4SLC6A3PTGDR2
SCHEMBL42935 0.81 PTGDR2 (0.58) HTR1ASLC6A2SLC6A4SLC6A3PTGDR2
SCHEMBL5159996 0.81 PTGDR2 (0.58) HTR1ASLC6A2SLC6A4SLC6A3PTGDR2
SCHEMBL2095683 0.80 SLC6A2 (0.48) HTR1ASLC6A2SLC6A4SLC6A3PTGDR2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 10 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-1261677-A1 THERMAL FLUID BLENDS CONTAINING 1, 2, 3, 4-TETRAHYDRO(1-PHENYLETHYL)NAPHTHALENE THE DOW CHEMICAL COMPANY (US) 2002-12-04 EP disclosed
US-6350927-B2 WITH ALKYL BIPHENYL TO PROVIDE HIGH TEMPERATURE HEAT TRANSFER FLUIDS EXHIBITING FAVORABLE THERMAL STABILITY THE DOW CHEMICAL COMPANY 2002-02-26 US disclosed
US-20010020117-A1 Thermal fluid blends containing 1,2,3,4- tetrahydro (1- phenylethyl)naphthalene DOW CHEMICAL COMPANY, THE 2001-09-06 US disclosed
WO-2001059029-A1 THERMAL FLUID BLENDS CONTAINING 1,2,3,4-TETRAHYDRO(1-PHENYLETHYL)NAPHTHALENE DOW GLOBAL TECHNOLOGIES INC. (US) 2001-08-16 WO disclosed
US-6239320-B1 HEAT EXCHANGE FLUID MIXTURE CONTAINING DIBENZYLTOLUENE THE DOW CHEMICAL COMPANY 2001-05-29 US disclosed
EP-0980410-A1 THERMAL FLUID BLENDS CONTAINING 1,2,3,4-TETRAHYDRO(1-PHENYLETHYL)NAPHTHALENE THE DOW CHEMICAL COMPANY (US) 2000-02-23 EP disclosed
WO-1998050483-A1 THERMAL FLUID BLENDS CONTAINING 1,2,3,4-TETRAHYDRO(1-PHENYLETHYL)NAPHTHALENE THE DOW CHEMICAL COMPANY (US) 1998-11-12 WO disclosed
EP-0599994-A1 PROCESS FOR THE PREPARATION OF PHENYLHYDROQUINONE EASTMAN KODAK COMPANY (US) 1994-06-08 EP disclosed
US-5210330-A Alkylating hydroquinone with cyclohexane in presence of acidic heterogeneous alkylation catalyst and solvent of biphenyl, diphenyl ether and/or methylnaphthalene; cooling; separating precipitated hydroquinone; catalytically dehydrogenating EASTMAN KODAK COMPANY (US) 1993-05-11 US disclosed
WO-1993004027-A1 PROCESS FOR THE PREPARATION OF PHENYLHYDROQUINONE EASTMAN KODAK COMPANY (US) 1993-03-04 WO disclosed