Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | RET | P07949 | 1/20 | 0.36 |
| ▸ | HTR2A | P28223 | 2/20 | 0.35 |
| ▸ | MAPT | P10636 | 1/20 | 0.33 |
| ▸ | CYP2D6 | P10635 | 2/20 | 0.33 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.33 |
| ▸ | HTR2C | P28335 | 2/20 | 0.33 |
| ▸ | LMNA | P02545 | 1/20 | 0.33 |
| ▸ | TP53 | P04637 | 1/20 | 0.33 |
| ▸ | CHRM2 | P08172 | 1/20 | 0.33 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.33 |
| ▸ | CHRM1 | P11229 | 1/20 | 0.33 |
| ▸ | DRD2 | P14416 | 1/20 | 0.33 |
| ▸ | ADRA2B | P18089 | 1/20 | 0.33 |
| ▸ | ADRA2C | P18825 | 1/20 | 0.33 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.33 |
| ▸ | CHRM3 | P20309 | 1/20 | 0.33 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.33 |
| ▸ | ADRA1A | P35348 | 1/20 | 0.33 |
| ▸ | HRH1 | P35367 | 1/20 | 0.33 |
| ▸ | DRD3 | P35462 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28935579 | 0.80 | CYP11B1 (0.40) | RETHTR2AMAPTCYP2D6KDM4E | |
| SCHEMBL30616031 | 0.80 | CYP11B1 (0.40) | RETHTR2AMAPTCYP2D6KDM4E | |
| SCHEMBL7608274 | 0.77 | HTR2A (0.37) | RETHTR2ACYP2D6KDM4EHTR2C | |
| SCHEMBL7046660 | 0.77 | HTR2A (0.38) | RETHTR2ACYP2D6KDM4EHTR2C | |
| SCHEMBL10827811 | 0.77 | HTR2A (0.38) | RETHTR2ACYP2D6KDM4EHTR2C | |
| SCHEMBL4273014 | 0.77 | HTR2A (0.38) | RETHTR2AMAPTCYP2D6KDM4E | |
| SCHEMBL6247077 | 0.74 | HTR2A (0.36) | RETHTR2ACYP2D6KDM4EHTR2C | |
| SCHEMBL3105168 | 0.74 | HTR2A (0.36) | RETHTR2ACYP2D6KDM4EHTR2C | |
| SCHEMBL27660579 | 0.73 | CYSLTR2 (0.39) | HTR2ACYP2D6KDM4EHTR2CLMNA | |
| SCHEMBL29479374 | 0.73 | RET (0.35) | RETHTR2AMAPTCYP2D6KDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-114634491-A | Polycyclic compound for inhibiting RNA helicase DHX33 | 成都开悦生命科技有限公司 | 2022-06-17 | — | — | CN | disclosed |
| CN-111217943-A | Spherical catalyst for olefin polymerization | 陈双云 | 2020-06-02 | — | — | CN | disclosed |
| EP-1260523-B1 | CATALYST SYSTEM FOR POLYMERIZATION AND COPOLYMERIZATION OF OLEFINS | CHINA PETROCHEMICAL CORP (CN) | 2013-01-23 | — | — | EP | disclosed |
| EP-1260523-A1 | CATALYST SYSTEM FOR POLYMERIZATION AND COPOLYMERIZATION OF OLEFINS | CHINA PETROCHEMICAL CORPORATION (CN) | 2002-11-27 | — | — | EP | disclosed |
| EP-0728770-B1 | Process for the preparation of solid catalyst components for the polymerization of olefins | MONTELL NORTH AMERICA INC (US) | 1999-07-14 | — | — | EP | disclosed |