Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HTR2A | P28223 | 2/20 | 0.37 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.37 |
| ▸ | LMNA | P02545 | 1/20 | 0.37 |
| ▸ | TP53 | P04637 | 1/20 | 0.37 |
| ▸ | CHRM2 | P08172 | 1/20 | 0.37 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.37 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.37 |
| ▸ | CHRM1 | P11229 | 1/20 | 0.37 |
| ▸ | DRD2 | P14416 | 1/20 | 0.37 |
| ▸ | ADRA2B | P18089 | 1/20 | 0.37 |
| ▸ | ADRA2C | P18825 | 1/20 | 0.37 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.37 |
| ▸ | CHRM3 | P20309 | 1/20 | 0.37 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.37 |
| ▸ | HTR2C | P28335 | 1/20 | 0.37 |
| ▸ | ADRA1A | P35348 | 1/20 | 0.37 |
| ▸ | HRH1 | P35367 | 1/20 | 0.37 |
| ▸ | DRD3 | P35462 | 1/20 | 0.37 |
| ▸ | THPO | P40225 | 1/20 | 0.37 |
| ▸ | OPRK1 | P41145 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL27660579 | 0.88 | CYSLTR2 (0.39) | HTR2AKDM4ELMNATP53CHRM2 | |
| SCHEMBL30616031 | 0.85 | CYP11B1 (0.40) | HTR2AKDM4ELMNATP53CHRM2 | |
| SCHEMBL28935579 | 0.85 | CYP11B1 (0.40) | HTR2AKDM4ELMNATP53CHRM2 | |
| SCHEMBL6247077 | 0.82 | HTR2A (0.36) | HTR2AKDM4ELMNATP53CHRM2 | |
| SCHEMBL4273014 | 0.78 | HTR2A (0.38) | HTR2AKDM4ELMNATP53CHRM2 | |
| SCHEMBL7046660 | 0.78 | HTR2A (0.38) | HTR2AKDM4ELMNATP53CHRM2 | |
| SCHEMBL10827811 | 0.78 | HTR2A (0.38) | HTR2AKDM4ELMNATP53CHRM2 | |
| SCHEMBL7598710 | 0.77 | RET (0.36) | HTR2AKDM4ELMNATP53CHRM2 | |
| SCHEMBL6962523 | 0.77 | KDM4E (0.33) | HTR2AKDM4ELMNATP53CHRM2 | |
| SCHEMBL3105168 | 0.75 | HTR2A (0.36) | HTR2AKDM4ELMNATP53CHRM2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-107085033-B | Application of the N- phenylnaphthalene aminated compounds as MALDI matrix | 中国科学院化学研究所 | 2019-07-19 | — | — | CN | disclosed |
| EP-1265848-A2 | AMINES SUBSTITUTED WITH A DIHYDRONAPHTHALENYL, CRHOMENYL, OR THIOCHROMENYL GROUP, AN ARYL OR HETEROARYL GROUP AND AN ALKYL GROUP, HAVING RETINOID-LIKE BIOLOGICAL ACTIVITY | Allergan Sales, Inc. (US) | 2002-12-18 | — | — | EP | disclosed |
| WO-2001070668-A2 | AMINES SUBSTITUTED WITH A DIHYDRONAPHTHALENYL, CRHOMENYL, OR THIOCHROMENYL GROUP, AN ARYL OR HETEROARYL GROUP AND AN ALKYL GROUP, HAVING RETINOID-LIKE BIOLOGICAL ACTIVITY | ALLERGAN, INC. (US) | 2001-09-27 | — | — | WO | disclosed |