Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GRIN2B | Q13224 | 4/20 | 0.44 |
| ▸ | GRIN1 | Q05586 | 5/20 | 0.43 |
| ▸ | GRIN2D | O15399 | 3/20 | 0.43 |
| ▸ | GRIN3B | O60391 | 3/20 | 0.43 |
| ▸ | GRIN2A | Q12879 | 3/20 | 0.43 |
| ▸ | GRIN2C | Q14957 | 3/20 | 0.43 |
| ▸ | GRIN3A | Q8TCU5 | 3/20 | 0.43 |
| ▸ | ENPP2 | Q13822 | 2/20 | 0.39 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.38 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.38 |
| ▸ | MEN1 | O00255 | 1/20 | 0.38 |
| ▸ | LMNA | P02545 | 1/20 | 0.38 |
| ▸ | MAPT | P10636 | 1/20 | 0.38 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.38 |
| ▸ | ATXN2 | Q99700 | 1/20 | 0.38 |
| ▸ | SSTR5 | P35346 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6160888 | 0.97 | GRIN2B (0.45) | GRIN2BGRIN1GRIN2DGRIN3BGRIN2A | |
| SCHEMBL6162230 | 0.95 | GRIN2B (0.48) | GRIN2BGRIN1GRIN2DGRIN3BGRIN2A | |
| Besonprodil SCHEMBL29388542 | 0.79 | GRIN1 (0.66) | GRIN2BGRIN1GRIN2DGRIN3BGRIN2A | |
| Besonprodil SCHEMBL2257896 | 0.79 | GRIN1 (0.66) | GRIN2BGRIN1GRIN2DGRIN3BGRIN2A | |
| SCHEMBL6163800 | 0.77 | GRIN1 (0.62) | GRIN2BGRIN1GRIN2DGRIN3BGRIN2A | |
| SCHEMBL15135313 | 0.75 | ENPP2 (0.46) | GRIN2BGRIN1GRIN2DGRIN3BGRIN2A | |
| SCHEMBL6162845 | 0.74 | HTR2A (0.45) | GRIN2BGRIN1GRIN2DGRIN3BGRIN2A | |
| SCHEMBL3446618 | 0.74 | GRIN2D (0.54) | GRIN2BGRIN1GRIN2DGRIN3BGRIN2A | |
| SCHEMBL6164799 | 0.72 | GRIN2B (0.48) | GRIN2BGRIN1GRIN2DGRIN3BGRIN2A | |
| SCHEMBL7190277 | 0.72 | GRIN1 (0.47) | GRIN2BGRIN1GRIN2DGRIN3BGRIN2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1254661-A1 | Method for preventing dyskinesias with selective NMDA-Antagonists | WARNER-LAMBERT COMPANY (US) | 2002-11-06 | — | — | EP | disclosed |