Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 4/20 | 0.39 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.39 |
| ▸ | THRB | P10828 | 1/20 | 0.39 |
| ▸ | EDNRA | P25101 | 1/20 | 0.39 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.38 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.38 |
| ▸ | LMNA | P02545 | 3/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.38 |
| ▸ | HPGD | P15428 | 2/20 | 0.38 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.38 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.38 |
| ▸ | HDAC8 | Q9BY41 | 1/20 | 0.38 |
| ▸ | PLA2G10 | O15496 | 1/20 | 0.38 |
| ▸ | GAA | P10253 | 1/20 | 0.38 |
| ▸ | RAB9A | P51151 | 1/20 | 0.38 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.38 |
| ▸ | SGMS2 | Q8NHU3 | 1/20 | 0.37 |
| ▸ | SLC1A5 | Q15758 | 1/20 | 0.37 |
| ▸ | SLC16A3 | O15427 | 1/20 | 0.37 |
| ▸ | SLC16A1 | P53985 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Hydrochloric Acid SCHEMBL7597575 | 0.99 | MAPT (0.39) | MAPTSMN1; SMN2THRBEDNRACYP1A2 | |
| SCHEMBL7066492 | 0.95 | MAPT (0.38) | MAPTSMN1; SMN2THRBEDNRACYP1A2 | |
| SCHEMBL7069540 | 0.94 | MAPT (0.39) | MAPTSMN1; SMN2THRBEDNRACYP1A2 | |
| SCHEMBL7066027 | 0.94 | MAPT (0.41) | MAPTSMN1; SMN2THRBEDNRALMNA | |
| SCHEMBL7603824 | 0.92 | LMNA (0.38) | MAPTSMN1; SMN2THRBEDNRACYP1A2 | |
| SCHEMBL7069471 | 0.92 | MAPT (0.40) | MAPTSMN1; SMN2THRBEDNRALMNA | |
| Hydrochloric Acid SCHEMBL7600294 | 0.91 | LMNA (0.38) | MAPTSMN1; SMN2THRBEDNRACYP1A2 | |
| SCHEMBL7066511 | 0.91 | PPARA (0.44) | MAPTSMN1; SMN2THRBEDNRACYP1A2 | |
| SCHEMBL7070063 | 0.90 | MAPT (0.40) | MAPTSMN1; SMN2THRBEDNRALMNA | |
| SCHEMBL7069288 | 0.90 | ICAM1 (0.38) | MAPTSMN1; SMN2THRBLMNAALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1266888-A1 | QUINOLINE DERIVATIVES AND MEDICINAL USE THEREOF | Mitsui Chemicals, Inc. (JP) | 2002-12-18 | — | — | EP | disclosed |