Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEN1 | O00255 | 1/20 | 0.45 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.45 |
| ▸ | GAA | P10253 | 1/20 | 0.45 |
| ▸ | CCR4 | P51679 | 2/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.41 |
| ▸ | CDC7 | O00311 | 1/20 | 0.40 |
| ▸ | CCNE1 | P24864 | 1/20 | 0.40 |
| ▸ | CDK2 | P24941 | 1/20 | 0.40 |
| ▸ | DBF4 | Q9UBU7 | 1/20 | 0.40 |
| ▸ | NR3C2 | P08235 | 3/20 | 0.38 |
| ▸ | ALOX12 | P18054 | 2/20 | 0.38 |
| ▸ | IKBKB | O14920 | 3/20 | 0.37 |
| ▸ | SIRT6 | Q8N6T7 | 1/20 | 0.37 |
| ▸ | GSK3B | P49841 | 1/20 | 0.34 |
| ▸ | LMNA | P02545 | 1/20 | 0.34 |
| ▸ | POLB | P06746 | 1/20 | 0.34 |
| ▸ | MAPT | P10636 | 1/20 | 0.34 |
| ▸ | HTT | P42858 | 1/20 | 0.34 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL26789793 | 0.79 | GAA (0.46) | MEN1KMT2AGAACCR4ALDH1A1 | |
| SCHEMBL943566 | 0.74 | MEN1 (0.47) | MEN1KMT2AGAACCR4ALDH1A1 | |
| Hydrochloric Acid SCHEMBL19552078 | 0.72 | MEN1 (0.46) | MEN1KMT2AGAACCR4ALDH1A1 | |
| SCHEMBL2787917 | 0.72 | PEPD (0.39) | MEN1KMT2AGAAALDH1A1NR3C2 | |
| SCHEMBL2629010 | 0.71 | MEN1 (0.45) | MEN1KMT2AGAACCR4ALDH1A1 | |
| SCHEMBL2215923 | 0.71 | CDC7 (0.46) | MEN1KMT2AGAAALDH1A1CDC7 | |
| SCHEMBL30496336 | 0.71 | CDC7 (0.46) | MEN1KMT2AGAAALDH1A1CDC7 | |
| SCHEMBL7544495 | 0.71 | CDC7 (0.39) | MEN1KMT2AGAACDC7CCNE1 | |
| Hydrochloric Acid SCHEMBL28897177 | 0.70 | MEN1 (0.44) | MEN1KMT2AGAACCR4ALDH1A1 | |
| SCHEMBL2629008 | 0.70 | MEN1 (0.44) | MEN1KMT2AGAACCR4ALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0889038-B1 | Process for the preparation of alkoxy-or aryloxypyrazine derivatives | LONZA AG (CH) | 2002-05-29 | — | — | EP | disclosed |