Predicted protein targets (top 3)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HRH3 | Q9Y5N1 | 20/20 | 0.90 |
| ▸ | HRH2 | P25021 | 1/20 | 0.66 |
| ▸ | HRH1 | P35367 | 1/20 | 0.66 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5217570 | 0.94 | HRH3 (1.00) | HRH3HRH2HRH1 | |
| SCHEMBL4089542 | 0.86 | HRH3 (0.97) | HRH3 | |
| Hydrochloric Acid SCHEMBL5935356 | 0.81 | HRH3 (0.87) | HRH3HRH1 | |
| SCHEMBL4619979 | 0.80 | HRH3 (0.70) | HRH3 | |
| SCHEMBL4621668 | 0.80 | HRH3 (0.70) | HRH3 | |
| Oxalic Acid SCHEMBL4498003 | 0.79 | HRH3 (0.66) | HRH3 | |
| Oxalic Acid SCHEMBL4508710 | 0.79 | HRH3 (0.66) | HRH3 | |
| SCHEMBL7593369 | 0.78 | HRH3 (0.66) | HRH3HRH2HRH1 | |
| SCHEMBL7594388 | 0.78 | HRH3 (0.66) | HRH3HRH2HRH1 | |
| SCHEMBL4670302 | 0.78 | HRH3 (0.72) | HRH3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20020111340-A1 | Aminoalkoxybiphenylcarboxamides as histamine-3 receptor ligands and their therapeutic applications | ABBOTT LABORATORIES | 2002-08-15 | — | — | US | claimed |
| US-6316475-B1 | TREATMENT OF CANCER, ASTHMA, HEART DISEASES, SEIZURES, INFLAMMATION | ABBOTT LABORATORIES | 2001-11-13 | — | — | US | claimed |
| US-20020111340-A1 | Aminoalkoxybiphenylcarboxamides as histamine-3 receptor ligands and their therapeutic applications | ABBOTT LABORATORIES | 2002-08-15 | — | — | US | disclosed |
| WO-2002040461-A2 | AMINOALKOXYBIPHENYL CARBOXAMIDES AS HISTAMINE-3 RECEPTOR LIGANDS AND THEIR THERAPEUTIC APPLICATIONS | ABBOTT LABORATORIES (US) | 2002-05-23 | — | — | WO | disclosed |
| US-6316475-B1 | TREATMENT OF CANCER, ASTHMA, HEART DISEASES, SEIZURES, INFLAMMATION | ABBOTT LABORATORIES | 2001-11-13 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20020111340-A1 | Aminoalkoxybiphenylcarboxamides as histamine-3 receptor ligands and their therapeutic applications | HRH3, HRH4, HRH2 | HRH3 1/4885HRH2 3/4885HRH1 4/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.