Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HRH3 | Q9Y5N1 | 18/20 | 0.66 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.56 |
| ▸ | HPGD | P15428 | 2/20 | 0.56 |
| ▸ | MEN1 | O00255 | 1/20 | 0.56 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.56 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.56 |
| ▸ | CHRM2 | P08172 | 1/20 | 0.53 |
| ▸ | CHRM1 | P11229 | 1/20 | 0.53 |
| ▸ | ADRA2C | P18825 | 1/20 | 0.53 |
| ▸ | CHRM3 | P20309 | 1/20 | 0.53 |
| ▸ | DRD4 | P21917 | 1/20 | 0.53 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.53 |
| ▸ | HRH2 | P25021 | 1/20 | 0.53 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.53 |
| ▸ | HRH1 | P35367 | 1/20 | 0.53 |
| ▸ | SLC6A3 | Q01959 | 1/20 | 0.53 |
| ▸ | HRH4 | Q9H3N8 | 1/20 | 0.53 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7594388 | 1.00 | HRH3 (0.66) | HRH3ALDH1A1HPGDMEN1KMT2A | |
| SCHEMBL5214588 | 0.83 | HRH3 (0.67) | HRH3ALDH1A1HPGDMEN1KMT2A | |
| SCHEMBL4089542 | 0.79 | HRH3 (0.97) | HRH3ALDH1A1HPGDMEN1KMT2A | |
| SCHEMBL7599273 | 0.78 | HRH3 (0.90) | HRH3HRH2HRH1 | |
| SCHEMBL7599220 | 0.78 | HRH3 (0.93) | HRH3ALDH1A1HPGDMEN1KMT2A | |
| SCHEMBL5216263 | 0.77 | HRH3 (0.76) | HRH3ALDH1A1HPGDMEN1KMT2A | |
| SCHEMBL5217570 | 0.77 | HRH3 (1.00) | HRH3HRH2HRH1 | |
| Bromide SCHEMBL7251230 | 0.76 | HRH3 (0.57) | HRH3ALDH1A1HPGDSMN1; SMN2 | |
| Bromide SCHEMBL7251226 | 0.76 | HRH3 (0.57) | HRH3ALDH1A1HPGDSMN1; SMN2 | |
| SCHEMBL7293014 | 0.74 | OXTR (0.64) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20020111340-A1 | Aminoalkoxybiphenylcarboxamides as histamine-3 receptor ligands and their therapeutic applications | ABBOTT LABORATORIES | 2002-08-15 | — | — | US | claimed |
| US-6316475-B1 | TREATMENT OF CANCER, ASTHMA, HEART DISEASES, SEIZURES, INFLAMMATION | ABBOTT LABORATORIES | 2001-11-13 | — | — | US | claimed |
| US-20020111340-A1 | Aminoalkoxybiphenylcarboxamides as histamine-3 receptor ligands and their therapeutic applications | ABBOTT LABORATORIES | 2002-08-15 | — | — | US | disclosed |
| US-6316475-B1 | TREATMENT OF CANCER, ASTHMA, HEART DISEASES, SEIZURES, INFLAMMATION | ABBOTT LABORATORIES | 2001-11-13 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20020111340-A1 | Aminoalkoxybiphenylcarboxamides as histamine-3 receptor ligands and their therapeutic applications | HRH3, HRH4, HRH2 | HRH3 1/4885ALDH1A1 702/4885HPGD 1298/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.