SCHEMBL7599539

SCHEMBL7599539

[Li]C1C(C)CCCC1CCCC

nearest known ligand 0.39

Predicted protein targets (top 11)

geneUniProtsupporting neighboursconfidence
CYP1A2 P05177 1/20 0.39
DPP4 P27487 4/20 0.36
NOS1 P29475 4/20 0.33
NOS2 P35228 4/20 0.33
NOS3 P29474 2/20 0.33
LMNA P02545 1/20 0.33
MAPK1 P28482 1/20 0.33
HTT P42858 1/20 0.33
CA1 P00915 1/20 0.32
CA2 P00918 1/20 0.32
CA4 P22748 1/20 0.32

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL7592391 0.88 CYP1A2 (0.37) CYP1A2DPP4NOS1NOS2NOS3
SCHEMBL7598282 0.88 CA1 (0.43) NOS1NOS2NOS3CA1CA2
SCHEMBL7594467 0.87 CYP1A2 (0.44) CYP1A2DPP4NOS1NOS2CA1
SCHEMBL16411400 0.83 CYP1A2 (0.44) CYP1A2DPP4NOS1NOS2NOS3
SCHEMBL7592388 0.82 CYP1A2 (0.40) CYP1A2DPP4NOS1NOS2CA1
SCHEMBL10453818 0.80 DPP4 (0.39) CYP1A2DPP4NOS1NOS2NOS3
SCHEMBL11903856 0.79 CYP1A2 (0.41) CYP1A2DPP4NOS1NOS2NOS3
SCHEMBL7594379 0.79 NOS3 (0.30) NOS1NOS2NOS3
SCHEMBL9949530 0.79 CYP1A2 (0.50) CYP1A2DPP4NOS1NOS2NOS3
SCHEMBL28598543 0.78 CYP1A2 (0.52) CYP1A2DPP4NOS1NOS2LMNA

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-0894802-B1 Silane compound NIPPON MITSUBISHI OIL CORP (JP) 2002-11-06 EP disclosed
US-6150549-A Silane compound NIPPON MITSUBISHI OIL CORPORATION (JP) 2000-11-21 US disclosed
EP-0894802-A2 Silane compound NIPPON OIL CO. LTD. (JP) 1999-02-03 EP disclosed