Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.44 |
| ▸ | S1PR4 | O95977 | 2/20 | 0.42 |
| ▸ | TAS1R3 | Q7RTX0 | 2/20 | 0.40 |
| ▸ | TAS1R1 | Q7RTX1 | 2/20 | 0.40 |
| ▸ | HTT | P42858 | 2/20 | 0.38 |
| ▸ | HDAC2 | Q92769 | 1/20 | 0.38 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.38 |
| ▸ | POLB | P06746 | 2/20 | 0.38 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.38 |
| ▸ | LMNA | P02545 | 1/20 | 0.38 |
| ▸ | NAMPT | P43490 | 1/20 | 0.37 |
| ▸ | HPGD | P15428 | 1/20 | 0.37 |
| ▸ | MEN1 | O00255 | 1/20 | 0.37 |
| ▸ | NPC1 | O15118 | 1/20 | 0.37 |
| ▸ | RAB9A | P51151 | 1/20 | 0.37 |
| ▸ | TP53 | P04637 | 1/20 | 0.36 |
| ▸ | THRB | P10828 | 1/20 | 0.36 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7598279 | 0.85 | HDAC2 (0.39) | TAS1R3TAS1R1HDAC2POLBKMT2A | |
| SCHEMBL7602524 | 0.84 | MEN1 (0.49) | TAS1R3TAS1R1HDAC2L3MBTL1KMT2A | |
| SCHEMBL7600512 | 0.84 | PDE4D (0.40) | TAS1R3TAS1R1KMT2ALMNAHPGD | |
| SCHEMBL7600479 | 0.81 | HPGD (0.41) | KDM4EHDAC2L3MBTL1POLBKMT2A | |
| SCHEMBL7603054 | 0.78 | KDM4E (0.40) | KDM4EHTTL3MBTL1POLBKMT2A | |
| SCHEMBL7598925 | 0.78 | CA1 (0.51) | TAS1R3TAS1R1HDAC2L3MBTL1POLB | |
| SCHEMBL3282351 | 0.74 | HDAC2 (0.45) | TAS1R3TAS1R1HDAC2POLBKMT2A | |
| SCHEMBL5031604 | 0.74 | POLB (0.50) | KDM4ETAS1R3TAS1R1HTTHDAC2 | |
| SCHEMBL12669228 | 0.71 | CA1 (0.50) | TAS1R3TAS1R1HDAC2L3MBTL1POLB | |
| SCHEMBL2307872 | 0.70 | S1PR4 (0.56) | KDM4ES1PR4HTTHDAC2L3MBTL1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0913713-B1 | Crosslinkable compound and an optical material employing it | MENICON CO LTD (JP) | 2002-12-18 | — | — | EP | disclosed |
| US-6015874-A | CURING AGENT FOR HYDROPHILIC, TRANSPARENT, DURABLE POLYMERIC CONTACT OR INTRAOCULAR LENSES WHICH ALSO ABSORB ULTRA VIOLET RADIATION AND ARE OXYGEN PERMEABLE | MENICON CO., LTD. (JP) | 2000-01-18 | — | — | US | disclosed |
| EP-0913713-A2 | Crosslinkable compound and an optical material employing it | Menicon Co., Ltd. (JP) | 1999-05-06 | — | — | EP | disclosed |