Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ITGB3 | P05106 | 13/20 | 0.79 |
| ▸ | ITGA2B | P08514 | 13/20 | 0.79 |
| ▸ | ITGAV | P06756 | 2/20 | 0.45 |
| ▸ | ACHE | P22303 | 1/20 | 0.37 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.36 |
| ▸ | HDAC8 | Q9BY41 | 1/20 | 0.36 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.36 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.36 |
| ▸ | LMNA | P02545 | 2/20 | 0.36 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.36 |
| ▸ | POLB | P06746 | 1/20 | 0.36 |
| ▸ | HPGD | P15428 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7593955 | 0.95 | ITGB3 (0.79) | ITGB3ITGA2BITGAVACHESMN1; SMN2 | |
| SCHEMBL7599947 | 0.88 | ITGB3 (1.00) | ITGB3ITGA2BITGAV | |
| SCHEMBL7600644 | 0.84 | ITGB3 (0.83) | ITGB3ITGA2BITGAVACHEALDH1A1 | |
| SCHEMBL7393761 | 0.84 | ITGB3 (0.83) | ITGB3ITGA2BITGAVACHEALDH1A1 | |
| SCHEMBL7399925 | 0.83 | ITGB3 (0.77) | ITGB3ITGA2BITGAVACHEALDH1A1 | |
| SCHEMBL7593946 | 0.83 | ITGB3 (1.00) | ITGB3ITGA2BITGAV | |
| SCHEMBL7595085 | 0.83 | ITGB3 (0.77) | ITGB3ITGA2BITGAVACHEALDH1A1 | |
| SCHEMBL7405763 | 0.82 | ITGB3 (0.89) | ITGB3ITGA2BITGAV | |
| SCHEMBL7596417 | 0.81 | ITGB3 (0.52) | ITGB3ITGA2BITGAVACHEHDAC1 | |
| SCHEMBL7397690 | 0.81 | ITGB3 (0.77) | ITGB3ITGA2BITGAV |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0593603-B1 | BICYCLIC FIBRINOGEN ANTAGONISTS | SMITHKLINE BEECHAM CORP (US) | 2002-11-20 | — | — | EP | claimed |
| EP-0593603-B1 | BICYCLIC FIBRINOGEN ANTAGONISTS | SMITHKLINE BEECHAM CORP (US) | 2002-11-20 | — | — | EP | disclosed |