Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MMP3 | P08254 | 1/20 | 0.42 |
| ▸ | BCL2L1 | Q07817 | 1/20 | 0.42 |
| ▸ | ESR1 | P03372 | 3/20 | 0.41 |
| ▸ | ESR2 | Q92731 | 3/20 | 0.41 |
| ▸ | NPC1 | O15118 | 2/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.41 |
| ▸ | HPGD | P15428 | 2/20 | 0.41 |
| ▸ | RAB9A | P51151 | 2/20 | 0.41 |
| ▸ | GAPDH | P04406 | 1/20 | 0.41 |
| ▸ | GAA | P10253 | 1/20 | 0.41 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.41 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.41 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.39 |
| ▸ | FTO | Q9C0B1 | 2/20 | 0.39 |
| ▸ | MAOA | P21397 | 1/20 | 0.39 |
| ▸ | MAOB | P27338 | 1/20 | 0.39 |
| ▸ | CTNNB1 | P35222 | 1/20 | 0.39 |
| ▸ | WNT3A | P56704 | 1/20 | 0.39 |
| ▸ | CA12 | O43570 | 5/20 | 0.38 |
| ▸ | CA9 | Q16790 | 5/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Benzofuran SCHEMBL18543658 | 0.93 | CA12 (0.48) | MMP3BCL2L1ESR1ESR2NPC1 | |
| Benzofuran SCHEMBL29415475 | 0.88 | — | — | |
| Benzofuran SCHEMBL29393518 | 0.88 | — | — | |
| Benzofuran SCHEMBL5564 | 0.88 | — | — | |
| Benzofuran SCHEMBL5834531 | 0.88 | MAOA (0.46) | FTOMAOAMAOBCTNNB1WNT3A | |
| Benzofuran SCHEMBL3160534 | 0.88 | — | — | |
| Benzofuran SCHEMBL28153539 | 0.86 | MAOA (0.41) | FTOMAOAMAOBCTNNB1WNT3A | |
| Benzofuran SCHEMBL118311 | 0.85 | CYP2A6 (0.45) | FTOMAOAMAOBCTNNB1WNT3A | |
| Benzofuran SCHEMBL11251534 | 0.85 | MAOA (0.44) | FTOMAOAMAOBCTNNB1WNT3A | |
| Benzofuran SCHEMBL1129070 | 0.85 | MAOA (0.44) | FTOMAOAMAOBCTNNB1WNT3A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1265840-A2 | NOVEL AMPHIPATHIC ALDEHYDES AND THEIR USE AS ADJUVANTS AND IMMUNOEFFECTORS | CORIXA CORPORATION (US) | 2002-12-18 | — | — | EP | disclosed |
| WO-2001070663-A2 | NOVEL AMPHIPATHIC ALDEHYDES AND THEIR USE AS ADJUVANTS AND IMMUNOEFFECTORS | CORIXA CORPORATION (US) | 2001-09-27 | — | — | WO | disclosed |