SCHEMBL7600368

SCHEMBL7600368

O=C(O)C1=CC=CC(C(=O)O)C1=O

nearest known ligand 0.33

Predicted protein targets (top 8)

geneUniProtsupporting neighboursconfidence
TSHR P16473 1/20 0.33
MAPK1 P28482 1/20 0.33
HSD17B10 Q99714 1/20 0.33
TDP1 Q9NUW8 1/20 0.33
THRB P10828 1/20 0.32
BLM P54132 1/20 0.32
PMP22 Q01453 1/20 0.32
KMT2A Q03164 1/20 0.32

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL11904680 0.78 TSHR (0.36) TSHRMAPK1HSD17B10TDP1THRB
SCHEMBL1651760 0.75 TSHR (0.33) TSHRMAPK1HSD17B10TDP1THRB
SCHEMBL1651762 0.75
SCHEMBL8637321 0.75 TSHR (0.33) TSHRMAPK1HSD17B10TDP1THRB
SCHEMBL4349424 0.75 TSHR (0.31) TSHRMAPK1HSD17B10TDP1THRB
SCHEMBL9096907 0.75 TSHR (0.31) TSHRMAPK1HSD17B10TDP1THRB
SCHEMBL9575751 0.73 TSHR (0.32) TSHRMAPK1HSD17B10TDP1THRB
Lithium SCHEMBL7518079 0.73 TSHR (0.30) TSHRMAPK1HSD17B10TDP1
SCHEMBL27704000 0.73 TSHR (0.38) TSHRMAPK1HSD17B10TDP1THRB
SCHEMBL7601207 0.72

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 21 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
JP-58092445-A None JP disclosed
JP-55064803-A None JP disclosed
EP-2651907-A1 BLEACH CATALYSTS BASF SE (DE) 2013-10-23 EP disclosed
WO-2012080088-A1 BLEACH CATALYSTS BASF SE (DE) 2012-06-21 WO disclosed
EP-1263414-A1 PHARMACEUTICAL COMPOSITIONS OF GLYCOGEN PHOSPHORYLASE INHIBITORS Pfizer Products Inc. (US) 2002-12-11 EP disclosed
EP-0879846-B1 Glass fiber filled polyester polymers M & G POLIMERI ITALIA SPA (IT) 2002-10-23 EP disclosed
WO-2001068055-A1 PHARMACEUTICAL COMPOSITIONS OF GLYCOGEN PHOSPHORYLASE INHIBITORS PFIZER PRODUCTS INC. (US) 2001-09-20 WO disclosed
CN-1307616-A Mixed polymer composition comprising crystallizable polyester polymer composition and aromatic polycarbonate, and foamable composition and closed cell polymer foam made therefrom M & G POLYMER ITALIA S P A (IT) 2001-08-08 CN disclosed
US-6214897-B1 FOAMABLE BLEND; CONTAINING BLOWING AGENT SHELL OIL COMPANY 2001-04-10 US disclosed
EP-1064327-A1 A MIXED POLYMER COMPOSITION COMPRISING A CRYSTALLIZABLE POLYESTER POLYMER COMPOSITION AND AN AROMATIC POLYCARBONATE; AND FOAMABLE COMPOSITIONS AND THE CLOSED CELL POLYMER FOAMS MADE THEREFROM Sipet Societa' Italiana Polietilene Tereftalato S.P.A. (IT) 2001-01-03 EP disclosed
US-6080824-A BLEND OF SEMICRYSTALLINE POLYCONDENSED BRANCHED POLYESTER, AND A NON-HALOGENATED AROMATIC POLYCARBONATE IN GIVEN WEIGHTS; HIGH EXTRUSION MELT STRENGTH; USE AS FOAM POLYESTER SHEET WITH LOWER DENSITY BUT HIGHER IMPACT STRENGTH SHELL OIL COMPANY (US) 2000-06-27 US disclosed
US-6025405-A Compositions of polycondensed branched polyester polymers and aromatic polycarbonates, and the closed cell polymer foams made therefrom SHELL OIL COMPANY (US) 2000-02-15 US disclosed
US-5997763-A AN ALKYLENE GLYCOL; BENZOIC ACID; AND AN EFFECTIVE CORROSION INHIBITING AMOUNT, OR MORE, OF A C7-C14 MONOCARBOXYLIC ACID. SHELL OIL COMPANY (US) 1999-12-07 US disclosed
WO-1999047603-A1 A MIXED POLYMER COMPOSITION COMPRISING A CRYSTALLIZABLE POLYESTER POLYMER COMPOSITION AND AN AROMATIC POLYCARBONATE; AND FOAMABLE COMPOSITIONS AND THE CLOSED CELL POLYMER FOAMS MADE THEREFROM SIPET SOCIETA' ITALIANA POLIETILENE TEREFTALATO S.P.A. (NL) 1999-09-23 WO disclosed
EP-0879846-A1 Glass fiber filled polyester polymers SHELL INTERNATIONALE RESEARCHMAATSCHAPPIJ B.V. (NL) 1998-11-25 EP disclosed
US-5780539-A ADDING GLASS FIBERS IMPROVES CRYSTALLIZATION TIMES DURING COOLING SHELL OIL COMPANY (US) 1998-07-14 US disclosed
EP-0268240-A2 Unsaturated copolymer resin composite MITSUBISHI PETROCHEMICAL CO., LTD. (JP) 1988-05-25 EP disclosed
JP-S5892445-A SELECTIVE PERMEABLE MEMBRANE FOR GAS SEPARATION TEIJIN LTD 1983-06-01 JP disclosed
JP-S5564803-A SELECTIVE PERMEABLE MEMBRANE FOR GAS SEPARATION TEIJIN LTD 1980-05-15 JP disclosed
US-4196279-A BORANE OR METAL TETRAHYDROCARBYLBORON TEIJIN LIMITED (JP) 1980-04-01 US disclosed