Predicted protein targets (top 8)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 1/20 | 0.32 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.32 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.32 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.32 |
| ▸ | THRB | P10828 | 1/20 | 0.32 |
| ▸ | BLM | P54132 | 1/20 | 0.32 |
| ▸ | PMP22 | Q01453 | 1/20 | 0.32 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6425979 | 0.84 | PPARG (0.38) | TSHR | |
| SCHEMBL7600368 | 0.73 | TSHR (0.33) | TSHRMAPK1HSD17B10TDP1THRB | |
| SCHEMBL1651760 | 0.73 | TSHR (0.33) | TSHRMAPK1HSD17B10TDP1THRB | |
| SCHEMBL8637321 | 0.73 | TSHR (0.33) | TSHRMAPK1HSD17B10TDP1THRB | |
| SCHEMBL9996000 | 0.68 | TSHR (0.30) | TSHRMAPK1HSD17B10TDP1 | |
| SCHEMBL3012580 | 0.65 | HTR7 (0.35) | KMT2A | |
| SCHEMBL19750859 | 0.62 | TSHR (0.35) | TSHRMAPK1HSD17B10TDP1 | |
| SCHEMBL11904680 | 0.60 | TSHR (0.36) | TSHRMAPK1HSD17B10TDP1THRB | |
| SCHEMBL4349424 | 0.58 | TSHR (0.31) | TSHRMAPK1HSD17B10TDP1THRB | |
| SCHEMBL27723749 | 0.58 | TSHR (0.41) | TSHR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0547809-A1 | Thermoplastic compositions | GENERAL ELECTRIC COMPANY (US) | 1993-06-23 | — | — | EP | disclosed |