SCHEMBL7600517

SCHEMBL7600517

CC(C)(c1c(F)c(F)c(F)c(C(=O)NN)c1C(=O)NN)c1c(F)c(F)c(F)c(C(=O)NN)c1C(=O)NN

nearest known ligand 0.41

Predicted protein targets (top 17)

geneUniProtsupporting neighboursconfidence
HTT P42858 3/20 0.41
RECQL P46063 1/20 0.39
PKM P14618 1/20 0.37
SMN1; SMN2 Q16637 1/20 0.37
TAS1R3 Q7RTX0 4/20 0.34
TAS1R1 Q7RTX1 4/20 0.34
TAS1R2 Q8TE23 4/20 0.34
KDM4E B2RXH2 1/20 0.33
CA1 P00915 3/20 0.32
CA2 P00918 3/20 0.32
TSHR P16473 1/20 0.32
LMNA P02545 1/20 0.32
TP53 P04637 1/20 0.32
MAPK1 P28482 1/20 0.32
KDM4C Q9H3R0 1/20 0.31
GAA P10253 1/20 0.31
HSD17B10 Q99714 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL8570432 0.82 HTT (0.50) HTTRECQLPKMSMN1; SMN2TAS1R3
SCHEMBL7607496 0.77 HTT (0.56) HTTRECQLPKMSMN1; SMN2TAS1R3
SCHEMBL1635303 0.72 MEN1 (0.36) HTTRECQLPKMSMN1; SMN2TAS1R3
SCHEMBL30777257 0.72 MEN1 (0.36) HTTRECQLPKMSMN1; SMN2TAS1R3
SCHEMBL29671481 0.66 MEN1 (0.33) HTTPKMSMN1; SMN2TAS1R3TAS1R1
SCHEMBL28723691 0.64 KDM4E (0.44) HTTRECQLSMN1; SMN2KDM4ECA1
SCHEMBL21467797 0.64 CES2 (0.37) HTTRECQLPKMSMN1; SMN2TAS1R3
SCHEMBL18177846 0.63 HTT (0.45) HTTRECQLPKMSMN1; SMN2TAS1R3
SCHEMBL18491201 0.62 MEN1 (0.36) HTTRECQLPKMSMN1; SMN2TAS1R3
SCHEMBL9425021 0.61 CA1 (0.52) HTTRECQLKDM4ECA1CA2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-0820805-B1 Use of a polyhydrazidoimide membrane for the seperation of air DAINIPPON INK & CHEMICALS (JP) 2002-09-04 EP disclosed
US-5972080-A STRENGTH, DURABILITY, SOLVENT RESISTANCE, HEAT RESISTANCE; GAS SEPARATION DAINIPPON INK AND CHEMICALS, INC. (JP) 1999-10-26 US disclosed
EP-0820805-A2 Separation membrane DAINIPPON INK AND CHEMICALS, INC. (JP) 1998-01-28 EP disclosed