Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.60 |
| ▸ | POLB | P06746 | 1/20 | 0.56 |
| ▸ | TSHR | P16473 | 2/20 | 0.55 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.55 |
| ▸ | ATM | Q13315 | 1/20 | 0.55 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.52 |
| ▸ | HPGD | P15428 | 1/20 | 0.52 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.52 |
| ▸ | TACR1 | P25103 | 1/20 | 0.51 |
| ▸ | OPRD1 | P41143 | 1/20 | 0.48 |
| ▸ | OPRK1 | P41145 | 1/20 | 0.48 |
| ▸ | GPR119 | Q8TDV5 | 1/20 | 0.47 |
| ▸ | GAA | P10253 | 1/20 | 0.47 |
| ▸ | PKM | P14618 | 1/20 | 0.46 |
| ▸ | CCR5 | P51681 | 2/20 | 0.44 |
| ▸ | CNR1 | P21554 | 1/20 | 0.44 |
| ▸ | CNR2 | P34972 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8364745 | 0.86 | TSHR (0.52) | ALDH1A1POLBTSHRALOX15ATM | |
| SCHEMBL8364780 | 0.84 | TSHR (0.50) | ALDH1A1POLBTSHRALOX15ATM | |
| SCHEMBL4630124 | 0.84 | TSHR (0.50) | ALDH1A1POLBTSHRALOX15ATM | |
| SCHEMBL28872311 | 0.84 | TSHR (0.54) | ALDH1A1TSHRALOX15ATMKDM4E | |
| SCHEMBL7375713 | 0.83 | TSHR (0.49) | ALDH1A1POLBTSHRALOX15ATM | |
| SCHEMBL4631302 | 0.83 | ALDH1A1 (0.60) | ALDH1A1TSHRALOX15ATMTACR1 | |
| SCHEMBL13774961 | 0.82 | ALDH1A1 (0.71) | ALDH1A1POLBKDM4EHPGDHSD17B10 | |
| SCHEMBL8364603 | 0.82 | EPHX1 (0.57) | POLBTSHRALOX15ATMKDM4E | |
| SCHEMBL13543984 | 0.80 | TSHR (0.64) | TSHRALOX15ATMKDM4EHSD17B10 | |
| SCHEMBL14485601 | 0.80 | POLB (0.63) | ALDH1A1POLBKDM4EHPGDHSD17B10 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0915849-A2 | PROCESS FOR THE PREPARATION OF 3,3-DISUBSTITUTED PIPERIDINES | Smithkline Beecham S.p.A. (IT) | 1999-05-19 | — | — | EP | disclosed |
| WO-1998005640-A2 | PROCESS FOR THE PREPARATION OF 3,3-DISUBSTITUTED PIPERIDINES | SMITHKLINE BEECHAM S.P.A. (IT) | 1998-02-12 | — | — | WO | disclosed |