Predicted protein targets (top 8)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MMP9 | P14780 | 20/20 | 0.73 |
| ▸ | MMP2 | P08253 | 17/20 | 0.73 |
| ▸ | MMP1 | P03956 | 7/20 | 0.73 |
| ▸ | MMP3 | P08254 | 1/20 | 0.57 |
| ▸ | MMP7 | P09237 | 1/20 | 0.57 |
| ▸ | MMP8 | P22894 | 1/20 | 0.57 |
| ▸ | MMP13 | P45452 | 1/20 | 0.57 |
| ▸ | MMP14 | P50281 | 1/20 | 0.45 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7599805 | 1.00 | MMP9 (0.73) | MMP9MMP2MMP1MMP3MMP7 | |
| SCHEMBL7599807 | 1.00 | MMP9 (0.73) | MMP9MMP2MMP1MMP3MMP7 | |
| SCHEMBL7600745 | 0.89 | MMP9 (0.71) | MMP9MMP2MMP1MMP3MMP7 | |
| SCHEMBL7599560 | 0.88 | MMP9 (0.72) | MMP9MMP2MMP1MMP3MMP7 | |
| SCHEMBL7595612 | 0.88 | MMP9 (0.72) | MMP9MMP2MMP1MMP3MMP7 | |
| SCHEMBL7599348 | 0.88 | MMP9 (0.72) | MMP9MMP2MMP1MMP3MMP7 | |
| SCHEMBL7599063 | 0.88 | MMP9 (0.72) | MMP9MMP2MMP1MMP3MMP7 | |
| SCHEMBL7595722 | 0.88 | MMP9 (0.72) | MMP9MMP2MMP1MMP3MMP7 | |
| SCHEMBL7594938 | 0.85 | MMP9 (0.67) | MMP9MMP2MMP1MMP3MMP7 | |
| SCHEMBL7594936 | 0.85 | MMP9 (1.00) | MMP9MMP2MMP1MMP3MMP7 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1147101-B1 | REVERSE HYDROXAMATE INHIBITORS OF MATRIX METALLOPROTEINASES | ABBOTT LAB (US) | 2002-11-20 | — | — | EP | claimed |