Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KMT2A | Q03164 | 2/20 | 0.52 |
| ▸ | PGR | P06401 | 1/20 | 0.43 |
| ▸ | C3AR1 | Q16581 | 7/20 | 0.41 |
| ▸ | HRH3 | Q9Y5N1 | 1/20 | 0.40 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.40 |
| ▸ | LMNA | P02545 | 1/20 | 0.39 |
| ▸ | TP53 | P04637 | 2/20 | 0.38 |
| ▸ | PTGES | O14684 | 2/20 | 0.38 |
| ▸ | POLB | P06746 | 1/20 | 0.37 |
| ▸ | MEN1 | O00255 | 1/20 | 0.37 |
| ▸ | GAA | P10253 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7604005 | 0.93 | KMT2A (0.49) | KMT2APGRC3AR1HRH3SMN1; SMN2 | |
| SCHEMBL7605782 | 0.92 | KMT2A (0.54) | KMT2APGRC3AR1HRH3SMN1; SMN2 | |
| SCHEMBL7604162 | 0.92 | KMT2A (0.54) | KMT2APGRC3AR1HRH3SMN1; SMN2 | |
| SCHEMBL13660622 | 0.86 | KMT2A (0.52) | KMT2APGRC3AR1HRH3SMN1; SMN2 | |
| SCHEMBL7606071 | 0.86 | KMT2A (0.52) | KMT2APGRC3AR1HRH3SMN1; SMN2 | |
| SCHEMBL7606103 | 0.86 | KMT2A (0.52) | KMT2APGRC3AR1HRH3SMN1; SMN2 | |
| SCHEMBL1193476 | 0.86 | C3AR1 (0.40) | KMT2AC3AR1PTGES | |
| SCHEMBL7603999 | 0.85 | KMT2A (0.51) | KMT2APGRC3AR1HRH3SMN1; SMN2 | |
| SCHEMBL7601792 | 0.85 | KMT2A (0.51) | KMT2APGRC3AR1HRH3SMN1; SMN2 | |
| SCHEMBL13660621 | 0.84 | KMT2A (0.55) | KMT2APGRC3AR1HRH3SMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2268625-B1 | OXO-HETEROCYCLIC SUBSTITUTED CARBOXYLIC ACID DERIVATES AND THE USE THEREOF | Bayer Pharma AG (DE) | 2012-05-16 | — | — | EP | disclosed |