Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KMT2A | Q03164 | 2/20 | 0.51 |
| ▸ | PGR | P06401 | 1/20 | 0.42 |
| ▸ | C3AR1 | Q16581 | 9/20 | 0.41 |
| ▸ | HRH3 | Q9Y5N1 | 1/20 | 0.41 |
| ▸ | PDE4A | P27815 | 1/20 | 0.40 |
| ▸ | PDE4B | Q07343 | 1/20 | 0.40 |
| ▸ | PDE4C | Q08493 | 1/20 | 0.40 |
| ▸ | PDE4D | Q08499 | 1/20 | 0.40 |
| ▸ | PDE3B | Q13370 | 1/20 | 0.40 |
| ▸ | PDE3A | Q14432 | 1/20 | 0.40 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.40 |
| ▸ | THRB | P10828 | 1/20 | 0.39 |
| ▸ | TP53 | P04637 | 1/20 | 0.39 |
| ▸ | POLB | P06746 | 1/20 | 0.38 |
| ▸ | MEN1 | O00255 | 1/20 | 0.38 |
| ▸ | GAA | P10253 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7603999 | 1.00 | KMT2A (0.51) | KMT2APGRC3AR1HRH3PDE4A | |
| SCHEMBL7604005 | 0.93 | KMT2A (0.49) | KMT2APGRC3AR1HRH3PDE4A | |
| SCHEMBL7605782 | 0.92 | KMT2A (0.54) | KMT2APGRC3AR1HRH3SMN1; SMN2 | |
| SCHEMBL7604162 | 0.92 | KMT2A (0.54) | KMT2APGRC3AR1HRH3SMN1; SMN2 | |
| SCHEMBL13660706 | 0.89 | KMT2A (0.45) | KMT2APGRHRH3PDE4APDE4B | |
| SCHEMBL7605723 | 0.89 | KMT2A (0.45) | KMT2APGRHRH3PDE4APDE4B | |
| SCHEMBL7605539 | 0.88 | KMT2A (0.45) | KMT2APGRHRH3PDE4APDE4B | |
| SCHEMBL1177782 | 0.87 | C3AR1 (0.40) | KMT2AC3AR1 | |
| SCHEMBL1178118 | 0.87 | C3AR1 (0.40) | KMT2AC3AR1 | |
| SCHEMBL1177785 | 0.87 | C3AR1 (0.40) | KMT2AC3AR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2268625-B1 | OXO-HETEROCYCLIC SUBSTITUTED CARBOXYLIC ACID DERIVATES AND THE USE THEREOF | Bayer Pharma AG (DE) | 2012-05-16 | — | — | EP | disclosed |