Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | FGFR1 | P11362 | 2/20 | 0.57 |
| ▸ | SLC22A6 | Q4U2R8 | 2/20 | 0.57 |
| ▸ | POLB | P06746 | 4/20 | 0.47 |
| ▸ | POLA1 | P09884 | 2/20 | 0.45 |
| ▸ | POLG | P54098 | 2/20 | 0.45 |
| ▸ | HPRT1 | P00492 | 6/20 | 0.43 |
| ▸ | TYMP | P19971 | 1/20 | 0.43 |
| ▸ | PNP | P00491 | 2/20 | 0.39 |
| ▸ | ABCB11 | O95342 | 1/20 | 0.39 |
| ▸ | FAP | Q12884 | 1/20 | 0.39 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2607253 | 0.87 | SLC22A6 (0.62) | FGFR1SLC22A6POLBPOLA1POLG | |
| SCHEMBL7591142 | 0.83 | HPRT1 (0.52) | FGFR1SLC22A6POLBPOLA1POLG | |
| SCHEMBL15449788 | 0.82 | FGFR1 (0.73) | FGFR1SLC22A6POLBPOLA1POLG | |
| Pmedap SCHEMBL215611 | 0.77 | FGFR1 (0.72) | FGFR1SLC22A6POLBPOLA1POLG | |
| Pmedap SCHEMBL29571667 | 0.77 | FGFR1 (0.72) | FGFR1SLC22A6POLBPOLA1POLG | |
| SCHEMBL2606890 | 0.76 | POLB (0.49) | FGFR1SLC22A6POLBPOLA1POLG | |
| SCHEMBL30759944 | 0.76 | FGFR1 (0.63) | FGFR1SLC22A6POLBPOLA1POLG | |
| SCHEMBL1566036 | 0.76 | FGFR1 (0.63) | FGFR1SLC22A6POLBPOLA1POLG | |
| SCHEMBL30824623 | 0.75 | FGFR1 (0.60) | FGFR1SLC22A6POLBPOLA1POLG | |
| SCHEMBL1567494 | 0.75 | FGFR1 (0.60) | FGFR1SLC22A6POLBPOLA1POLG |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0919562-B1 | PHOSPHONATE NUCLEOTIDE COMPOUNDS | MITSUBISHI CHEM CORP (JP) | 2002-11-06 | — | — | EP | disclosed |