Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | FGFR1 | P11362 | 3/20 | 0.69 |
| ▸ | SLC22A6 | Q4U2R8 | 2/20 | 0.69 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.56 |
| ▸ | TSHR | P16473 | 1/20 | 0.56 |
| ▸ | POLA1 | P09884 | 2/20 | 0.47 |
| ▸ | POLG | P54098 | 2/20 | 0.47 |
| ▸ | ABCB11 | O95342 | 1/20 | 0.47 |
| ▸ | FAP | Q12884 | 1/20 | 0.47 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.45 |
| ▸ | TYMP | P19971 | 1/20 | 0.43 |
| ▸ | POLB | P06746 | 2/20 | 0.41 |
| ▸ | ENPP1 | P22413 | 1/20 | 0.41 |
| ▸ | HPRT1 | P00492 | 2/20 | 0.40 |
| ▸ | P2RY1 | P47900 | 1/20 | 0.40 |
| ▸ | FDPS | P14324 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL15449788 | 0.84 | FGFR1 (0.73) | FGFR1SLC22A6POLA1POLGABCB11 | |
| Adefovir SCHEMBL49373 | 0.81 | FGFR1 (1.00) | FGFR1SLC22A6POLA1POLGABCB11 | |
| Adefovir SCHEMBL29365535 | 0.81 | FGFR1 (1.00) | FGFR1SLC22A6POLA1POLGABCB11 | |
| SCHEMBL15045868 | 0.81 | FGFR1 (0.69) | FGFR1SLC22A6POLA1POLGABCB11 | |
| Adefovir SCHEMBL28571494 | 0.81 | FGFR1 (0.97) | FGFR1SLC22A6POLA1POLGABCB11 | |
| Adefovir SCHEMBL3639260 | 0.81 | FGFR1 (0.97) | FGFR1SLC22A6POLA1POLGABCB11 | |
| Adefovir SCHEMBL28511793 | 0.81 | FGFR1 (0.97) | FGFR1SLC22A6POLA1POLGABCB11 | |
| Adefovir SCHEMBL29064626 | 0.81 | FGFR1 (0.97) | FGFR1SLC22A6POLA1POLGABCB11 | |
| Adefovir SCHEMBL439995 | 0.81 | FGFR1 (0.97) | FGFR1SLC22A6POLA1POLGABCB11 | |
| Adefovir SCHEMBL3643715 | 0.81 | FGFR1 (0.97) | FGFR1SLC22A6POLA1POLGABCB11 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0919562-B1 | PHOSPHONATE NUCLEOTIDE COMPOUNDS | MITSUBISHI CHEM CORP (JP) | 2002-11-06 | — | — | EP | disclosed |