SCHEMBL7601496

SCHEMBL7601496

C#CC1(C=O)CCCCC1

nearest known ligand 0.31

Predicted protein targets (top 3)

geneUniProtsupporting neighboursconfidence
MEN1 O00255 1/20 0.31
POLB P06746 1/20 0.31
KMT2A Q03164 1/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL2290605 0.74 MEN1 (0.31) MEN1POLBKMT2A
SCHEMBL1230678 0.74 ALDH1A1 (0.40)
SCHEMBL28187002 0.74 ALDH1A1 (0.40)
SCHEMBL4121119 0.70
SCHEMBL10332170 0.65
SCHEMBL2105263 0.64
SCHEMBL13964903 0.64 MEN1 (0.44) MEN1POLBKMT2A
SCHEMBL1964800 0.63
SCHEMBL6171621 0.62
SCHEMBL547851 0.61

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 15 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-2738172-A1 New bicyclic compounds as crac channel modulators Almirall, S.A. (ES) 2014-06-04 EP disclosed
EP-1060294-B1 METHOD FOR CARBOXYLATING TERMINAL ALKYNES KARLSRUHE FORSCHZENT (DE) 2002-12-18 EP disclosed
US-6342149-B1 REACTION OF CARBON DIOXIDE UNDER PRESSURE WITH ELECTROLYSIS FOR CARBONYLATION FORSCHUNGSZENTRUM KARLSRUHE (DE) 2002-01-29 US disclosed
EP-1060294-A1 METHOD FOR CARBOXYLATING TERMINAL ALKYNES Forschungszentrum Karlsruhe GmbH (DE) 2000-12-20 EP disclosed
WO-1999045173-A1 METHOD FOR CARBOXYLATING TERMINAL ALKYNES FORSCHUNGSZENTRUM KARLSRUHE GMBH (DE) 1999-09-10 WO disclosed
US-5502073-A INSECTICIDES OR ANTHELMINTICS THE WELLCOME FOUNDATION (GB) 1996-03-26 US disclosed
CN-1025677-C Novel heterocyclic pesticidal compounds WELLCOME FOUND (GB) 1994-08-17 CN disclosed
EP-0294229-B1 NOVEL HETEROCYCLIC PESTICIDAL COMPOUNDS THE WELLCOME FOUNDATION LIMITED (GB) 1992-12-02 EP disclosed
EP-0294228-B1 NOVEL HETEROCYCLIC PESTICIDAL COMPOUNDS THE WELLCOME FOUNDATION LIMITED (GB) 1992-08-26 EP disclosed
EP-0372816-B1 NOVEL HETEROCYCLIC PESTICIDAL COMPOUNDS THE WELLCOME FOUNDATION LIMITED (GB) 1992-07-29 EP disclosed
WO-1990006304-A1 NOVEL HETEROCYCLIC PESTICIDAL COMPOUNDS THE WELLCOME FOUNDATION LIMITED (GB) 1990-06-14 WO disclosed
EP-0372816-A1 Novel heterocyclic pesticidal compounds THE WELLCOME FOUNDATION LIMITED (GB) 1990-06-13 EP disclosed
CN-1030236-A NOVEL HETEROCYCLIC PESTICIDAL COMPOUNDS WELLCOME FOUND (GB) 1989-01-11 CN disclosed
EP-0294228-A2 Novel heterocyclic pesticidal compounds THE WELLCOME FOUNDATION LIMITED (GB) 1988-12-07 EP disclosed
EP-0294229-A2 Novel heterocyclic pesticidal compounds THE WELLCOME FOUNDATION LIMITED (GB) 1988-12-07 EP disclosed