Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GRIK1 | P39086 | 1/20 | 0.38 |
| ▸ | GRIK2 | Q13002 | 1/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.36 |
| ▸ | TSHR | P16473 | 1/20 | 0.36 |
| ▸ | EP300 | Q09472 | 1/20 | 0.35 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.31 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.31 |
| ▸ | LMNA | P02545 | 1/20 | 0.31 |
| ▸ | FFAR3 | O14843 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11650762 | 1.00 | GRIK1 (0.38) | GRIK1GRIK2ALDH1A1TSHREP300 | |
| SCHEMBL7601525 | 1.00 | GRIK1 (0.38) | GRIK1GRIK2ALDH1A1TSHREP300 | |
| SCHEMBL1486764 | 0.89 | GRIK1 (0.41) | GRIK1GRIK2ALDH1A1EP300FFAR3 | |
| SCHEMBL11600641 | 0.86 | EP300 (0.53) | EP300HSD17B10TDP1LMNA | |
| SCHEMBL11600639 | 0.86 | EP300 (0.53) | EP300HSD17B10TDP1LMNA | |
| SCHEMBL11599523 | 0.85 | EP300 (0.56) | EP300HSD17B10TDP1LMNA | |
| SCHEMBL11599339 | 0.85 | EP300 (0.56) | EP300HSD17B10TDP1LMNA | |
| SCHEMBL11599343 | 0.85 | EP300 (0.56) | EP300HSD17B10TDP1LMNA | |
| SCHEMBL11600354 | 0.85 | EP300 (0.56) | EP300HSD17B10TDP1LMNA | |
| SCHEMBL11599526 | 0.85 | EP300 (0.56) | EP300HSD17B10TDP1LMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 48 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4736063-A | OXIDATION OF ACETIC ACID AND BUTADIENE TO FORM ACETOXYHEXENOIC ACIDS; PURIFICATION AND ACID CATALYST CONVERSION | MONSANTO COMPANY (US) | 1988-04-05 | — | — | US | claimed |
| US-4564689-A | G-VINYL-G-BUTYROLACTONE FROM BUTADIENE AND ACETIC ACID, MANGANESE SALTS | MONSANTO COMPANY (US) | 1986-01-14 | — | — | US | claimed |
| US-4560775-A | REACTING BUTADIENE AND ACETIC ACID WITH A METAL SALT OXIDANT | MONSANTO COMPANY (US) | 1985-12-24 | — | — | US | claimed |
| EP-0060365-B1 | PROCESS FOR PRODUCING GAMMA-VINYL-GAMMA BUTYROLACTONE | MONSANTO COMPANY (US) | 1985-08-07 | — | — | EP | claimed |
| US-4526990-A | Reacting butadiene and acetic acid in the presence of metal ion oxidants | MONSANTO COMPANY (US) | 1985-07-02 | — | — | US | claimed |
| EP-0055934-B1 | ACYLOXY ALKENOIC ACIDS AND PROCESS THEREFOR | MONSANTO COMPANY (US) | 1985-03-13 | — | — | EP | claimed |
| EP-0055936-B1 | SORBIC ACID PROCESS | MONSANTO COMPANY (US) | 1984-09-05 | — | — | EP | claimed |
| US-4460787-A | COPPER OR SILVER COMPOUNDS | MONSANTO COMPANY (US) | 1984-07-17 | — | — | US | claimed |
| EP-0083914-A1 | Metal and acid catalysis in sorbic acid preparation | MONSANTO COMPANY (US) | 1983-07-20 | — | — | EP | claimed |
| US-4380650-A | Lactone process | MONSANTO COMPANY (US) | 1983-04-19 | — | — | US | claimed |
| US-4356317-A | REACTION OF BUTADIENE AND ACETIC ACID WITH METAL SALT OXIDANTS | MONSANTO COMPANY (US) | 1982-10-26 | — | — | US | claimed |
| EP-0060365-A2 | Process for producing gamma-vinyl-gamma butyrolactone | MONSANTO COMPANY (US) | 1982-09-22 | — | — | EP | claimed |
| EP-0055934-A2 | Acyloxy alkenoic acids and process therefor | MONSANTO COMPANY (US) | 1982-07-14 | — | — | EP | claimed |
| EP-0055935-A2 | Method for inhibiting growth of pathogens and spoilage organisms in foods and feeds; food and feed compositions containing a micro-organism inhibitor | MONSANTO COMPANY (US) | 1982-07-14 | — | — | EP | claimed |
| EP-0055936-A1 | Sorbic acid process | MONSANTO COMPANY (US) | 1982-07-14 | — | — | EP | claimed |
| US-20130045951-A1 | Novel Nitroso Compounds as Nitroxyl Donors and Methods of Use Thereof | CARDIOXYL PHARMACEUTICALS, INC. (US) | 2013-02-21 | — | — | US | disclosed |
| EP-1264818-A1 | A method for treating an effluent containing sorbic acid and/or a salt thereof and an effluent disposal device | Daicel Chemical Industries, Ltd. (JP) | 2002-12-11 | — | — | EP | disclosed |
| EP-0055935-A2 | Method for inhibiting growth of pathogens and spoilage organisms in foods and feeds; food and feed compositions containing a micro-organism inhibitor | MONSANTO COMPANY (US) | 1982-07-14 | — | — | EP | disclosed |
| EP-0055934-A2 | Acyloxy alkenoic acids and process therefor | MONSANTO COMPANY (US) | 1982-07-14 | — | — | EP | disclosed |
| EP-0055936-A1 | Sorbic acid process | MONSANTO COMPANY (US) | 1982-07-14 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20130045951-A1 | Novel Nitroso Compounds as Nitroxyl Donors and Methods of Use Thereof | NOXO1, TNNI3, HAO2 | GRIK1 2765/4885GRIK2 3227/4885ALDH1A1 624/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.