Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 1/20 | 0.34 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.33 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.33 |
| ▸ | GLO1 | Q04760 | 1/20 | 0.33 |
| ▸ | TSHR | P16473 | 1/20 | 0.32 |
| ▸ | LMNA | P02545 | 1/20 | 0.32 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.32 |
| ▸ | EGLN1 | Q9GZT9 | 1/20 | 0.32 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.31 |
| ▸ | MGAM | O43451 | 1/20 | 0.31 |
| ▸ | GAA | P10253 | 1/20 | 0.31 |
| ▸ | SI | P14410 | 1/20 | 0.31 |
| ▸ | MGAM2 | Q2M2H8 | 1/20 | 0.31 |
| ▸ | SOAT1 | P35610 | 1/20 | 0.31 |
| ▸ | FAAH | O00519 | 2/20 | 0.30 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.30 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28169656 | 0.80 | ALDH1A1 (0.46) | MAPTALDH1A1NPSR1GLO1TSHR | |
| SCHEMBL7597371 | 0.76 | — | — | |
| SCHEMBL10524661 | 0.74 | GAA (0.42) | MAPTALDH1A1NPSR1GLO1TSHR | |
| SCHEMBL736916 | 0.71 | ALDH1A1 (0.42) | MAPTALDH1A1NPSR1GLO1TSHR | |
| SCHEMBL252652 | 0.68 | ALDH1A1 (0.46) | ALDH1A1TSHR | |
| SCHEMBL28169657 | 0.68 | ALDH1A1 (0.39) | MAPTALDH1A1NPSR1GLO1TSHR | |
| SCHEMBL15864490 | 0.68 | ALDH1A1 (0.34) | MAPTALDH1A1NPSR1GLO1LMNA | |
| SCHEMBL15864696 | 0.68 | ALDH1A1 (0.34) | MAPTALDH1A1NPSR1GLO1LMNA | |
| SCHEMBL28762531 | 0.67 | ALDH1A1 (0.37) | MAPTALDH1A1NPSR1GLO1TSHR | |
| SCHEMBL706899 | 0.66 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1022302-B1 | Catalyst system, process and silicone compositions | HENKEL LOCTITE CORP (US) | 2002-12-04 | — | — | EP | disclosed |
| US-6140444-A | Catalyst system, process, and silicone compositions | LOCTITE CORPORATION (US) | 2000-10-31 | — | — | US | disclosed |
| EP-1022302-A2 | Catalyst system, process and silicone compositions | LOCTITE CORPORATION (US) | 2000-07-26 | — | — | EP | disclosed |