Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KMT2A | Q03164 | 2/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.38 |
| ▸ | GAA | P10253 | 1/20 | 0.38 |
| ▸ | THRB | P10828 | 1/20 | 0.38 |
| ▸ | PGR | P06401 | 1/20 | 0.36 |
| ▸ | MEN1 | O00255 | 1/20 | 0.35 |
| ▸ | MAOB | P27338 | 2/20 | 0.35 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.34 |
| ▸ | BACE1 | P56817 | 1/20 | 0.34 |
| ▸ | LMNA | P02545 | 1/20 | 0.33 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.33 |
| ▸ | PDE4B | Q07343 | 2/20 | 0.32 |
| ▸ | POLB | P06746 | 1/20 | 0.32 |
| ▸ | HTT | P42858 | 1/20 | 0.32 |
| ▸ | PDE4A | P27815 | 1/20 | 0.32 |
| ▸ | PDE4C | Q08493 | 1/20 | 0.32 |
| ▸ | PDE4D | Q08499 | 1/20 | 0.32 |
| ▸ | PDE3B | Q13370 | 1/20 | 0.32 |
| ▸ | PDE3A | Q14432 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7603996 | 0.91 | KMT2A (0.36) | KMT2AALDH1A1GAATHRBPGR | |
| SCHEMBL1177873 | 0.91 | KMT2A (0.39) | KMT2AALDH1A1GAATHRBPGR | |
| SCHEMBL7601976 | 0.89 | KMT2A (0.35) | KMT2AALDH1A1GAATHRBPGR | |
| SCHEMBL7605597 | 0.89 | KMT2A (0.35) | KMT2AALDH1A1GAATHRBPGR | |
| SCHEMBL3691213 | 0.84 | MAOB (0.35) | KMT2AALDH1A1GAATHRBPGR | |
| SCHEMBL517151 | 0.84 | KMT2A (0.37) | KMT2AALDH1A1GAATHRBPGR | |
| SCHEMBL3709062 | 0.82 | KMT2A (0.36) | KMT2AALDH1A1GAATHRBPGR | |
| SCHEMBL517440 | 0.82 | KMT2A (0.36) | KMT2AALDH1A1GAATHRBPGR | |
| SCHEMBL3701817 | 0.81 | KMT2A (0.35) | KMT2AALDH1A1GAATHRBPGR | |
| SCHEMBL1069711 | 0.81 | KMT2A (0.37) | KMT2AALDH1A1GAATHRBPGR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2268625-B1 | OXO-HETEROCYCLIC SUBSTITUTED CARBOXYLIC ACID DERIVATES AND THE USE THEREOF | Bayer Pharma AG (DE) | 2012-05-16 | — | — | EP | disclosed |