Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KMT2A | Q03164 | 2/20 | 0.35 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.34 |
| ▸ | GAA | P10253 | 2/20 | 0.34 |
| ▸ | THRB | P10828 | 1/20 | 0.34 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.34 |
| ▸ | PGR | P06401 | 1/20 | 0.33 |
| ▸ | MAOB | P27338 | 2/20 | 0.33 |
| ▸ | PDE4B | Q07343 | 1/20 | 0.32 |
| ▸ | LMNA | P02545 | 1/20 | 0.31 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.31 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.31 |
| ▸ | PKM | P14618 | 1/20 | 0.31 |
| ▸ | MEN1 | O00255 | 1/20 | 0.30 |
| ▸ | POLB | P06746 | 1/20 | 0.30 |
| ▸ | HTT | P42858 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7603996 | 0.92 | KMT2A (0.36) | KMT2AALDH1A1GAATHRBCYP2D6 | |
| SCHEMBL3709062 | 0.91 | KMT2A (0.36) | KMT2AALDH1A1GAATHRBCYP2D6 | |
| SCHEMBL7601875 | 0.89 | KMT2A (0.38) | KMT2AALDH1A1GAATHRBCYP2D6 | |
| SCHEMBL3703386 | 0.86 | KMT2A (0.32) | KMT2AALDH1A1GAATHRBPGR | |
| SCHEMBL7601976 | 0.85 | KMT2A (0.35) | KMT2AALDH1A1GAATHRBCYP2D6 | |
| SCHEMBL1080114 | 0.84 | SMN1; SMN2 (0.37) | GAAPGRLMNASMN1; SMN2POLB | |
| SCHEMBL517151 | 0.83 | KMT2A (0.37) | KMT2AALDH1A1GAATHRBCYP2D6 | |
| SCHEMBL1177873 | 0.82 | KMT2A (0.39) | KMT2AALDH1A1GAATHRBCYP2D6 | |
| SCHEMBL1178364 | 0.79 | PTGES (0.40) | MAOB | |
| SCHEMBL3701817 | 0.79 | KMT2A (0.35) | KMT2AALDH1A1GAATHRBCYP2D6 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2268625-B1 | OXO-HETEROCYCLIC SUBSTITUTED CARBOXYLIC ACID DERIVATES AND THE USE THEREOF | Bayer Pharma AG (DE) | 2012-05-16 | — | — | EP | disclosed |