SCHEMBL7601905

SCHEMBL7601905

O=C(O)c1cccc(Oc2ccccc2S(=O)(=O)c2ccccc2)c1C(=O)O

nearest known ligand 0.50

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
HTR6 P50406 2/20 0.50
MMP2 P08253 7/20 0.46
MMP9 P14780 7/20 0.46
MMP8 P22894 7/20 0.46
MMP13 P45452 7/20 0.46
MMP12 P39900 6/20 0.46
MMP14 P50281 5/20 0.46
MMP16 P51512 5/20 0.46
MMP3 P08254 5/20 0.46
MMP1 P03956 3/20 0.43
HTT P42858 1/20 0.42
CCR2 P41597 4/20 0.41
NPSR1 Q6W5P4 1/20 0.40
CCR1 P32246 1/20 0.40
CA1 P00915 1/20 0.40
CA2 P00918 1/20 0.40
FABP4 P15090 1/20 0.38
TSHR P16473 1/20 0.38
SMN1; SMN2 Q16637 1/20 0.38
ALDH1A1 P00352 1/20 0.38

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL28597961 0.93 HTT (0.45) HTR6MMP2MMP9MMP8MMP13
SCHEMBL29736476 0.93 HTT (0.45) HTR6MMP2MMP9MMP8MMP13
SCHEMBL7178253 0.91 HTR6 (0.43) HTR6MMP2MMP9MMP8MMP13
SCHEMBL28326658 0.85 HTT (0.47) MMP2MMP9MMP8MMP13MMP1
SCHEMBL29676384 0.83 NPSR1 (0.47) HTR6MMP2MMP9MMP8MMP13
SCHEMBL34677 0.83 NPSR1 (0.47) HTR6MMP2MMP9MMP8MMP13
SCHEMBL6003587 0.81 HTT (0.59) HTTCA1CA2TSHRSMN1; SMN2
SCHEMBL143861 0.81 HTT (0.53) HTTCA1CA2TSHRALDH1A1
SCHEMBL29395127 0.81 HTT (0.53) HTTCA1CA2TSHRALDH1A1
SCHEMBL10580602 0.80 HTT (0.49) HTR6MMP2MMP9MMP8MMP13

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 15 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-2707434-A1 SILICONE POLYETHERIMIDE COPOLYMERS SABIC Innovative Plastics IP B.V. (NL) 2014-03-19 EP disclosed
WO-2012167068-A1 STERILIZED POLYETHERIMIDE ARTICLES SABIC INNOVATIVE PLASTICS IP B.V. (NL) 2012-12-06 WO disclosed
WO-2012154966-A1 SILICONE POLYETHERIMIDE COPOLYMERS SABIC INNOVATIVE PLASTICS IP B.V. (NL) 2012-11-15 WO disclosed
US-6500904-B1 FROM THE COUPLING OF LOWER MOLECULAR WEIGHT FUNCTIONALIZED PRECURSOR POLYIMIDES GENERAL ELECTRIC COMPANY 2002-12-31 US disclosed
EP-0618945-A1 FIRE RETARDING THERMOFORMABLE BLENDS OF COPOLYMER RESINS. GEN ELECTRIC (US) 1994-10-12 EP disclosed
US-5013799-A Flexural strength, tensile strength, nylon GILES JR HAROLD F (US) 1991-05-07 US disclosed
US-4657987-A MOLDING MATERIALS; SHRINKAGE INHIBITION NONABSORBENT TO WATER GENERAL ELECTRIC COMPANY (US) 1987-04-14 US disclosed
EP-0131643-A1 Polyetherimide-polycarbonate blends GENERAL ELECTRIC COMPANY (US) 1985-01-23 EP disclosed
WO-1984004753-A1 POLYETHERIMIDE-POLYSULFIDE BLENDS GEN ELECTRIC (US) 1984-12-06 WO disclosed
WO-1984004752-A1 POLYETHERIMIDE-POLYCARBONATE BLENDS GEN ELECTRIC (US) 1984-12-06 WO disclosed
EP-0122305-A1 Polyetherimide-polyamide blends GENERAL ELECTRIC COMPANY (US) 1984-10-24 EP disclosed
EP-0122307-A1 Blends of polyetherimide and rubber modified vinyl aromatic polymers GENERAL ELECTRIC COMPANY (US) 1984-10-24 EP disclosed
WO-1984003895-A1 POLYETHERIMIDE-ACRYLATE COPOLYMER BLENDS GEN ELECTRIC (US) 1984-10-11 WO disclosed
WO-1984003899-A1 BLENDS OF POLYETHERIMIDES AND RUBBER MODIFIED VINYL AROMATIC POLYMERS GEN ELECTRIC (US) 1984-10-11 WO disclosed
US-4417044-A AROMATIC (ETHER ANHYDRIDE) WITH DIAMINE GENERAL ELECTRIC COMPANY (US) 1983-11-22 US disclosed